You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Furosemide versus ethacrynic acid in pediatric patients undergoing cardiac surgery: a randomized controlled trial
|
|---|---|
| Published in |
Critical Care, December 2015
|
| DOI | 10.1186/s13054-014-0724-5 |
| Pubmed ID | |
| Authors |
Zaccaria Ricci, Roberta Haiberger, Chiara Pezzella, Cristiana Garisto, Isabella Favia, Paola Cogo |
| Abstract |
IntroductionClinical effects of Furosemide (F) and ethacrynic acid (EA) continuous infusion on urine output (UO), fluid balance and renal, cardiac, respiratory and metabolic function were compared in infants undergoing surgery for congenital heart diseases.MethodsA prospective randomized double-blinded study was conducted. Patients received either 0.2 mg/kg/h (up to 0.8 mg/kg/h) of F or EA.ResultsIn total 38 patients were enrolled in the F group and 36 in the EA group. No adverse reactions were recorded. UO at post-operative day (POD) 0 was significantly higher in the EA group, 6.9(3.3) ml/kg/h, compared to the F group, 4.6(2.3) ml/kg/h (P¿=¿0.002) but tended to be similar in the two groups thereafter. Mean administered F dose was 0.33(0.19) mg/kg/h compared to 0.22(0.13) mg/kg/h of EA (P <0.0001). Fluid balance was significantly more negative in the EA group at post-operative day 0: ¿43(54) ml/kg/h versus ¿17(32) ml/kg/h in the F group (P¿=¿0.01). Serum creatinine, Cystatin C and Neutrophil Gelatinase Associated Lipocalin levels and incidence of acute kidney injury did not show significant differences between groups. Metabolic alkalosis occurred frequently (about 70% of cases) in both groups but mean bicarbonate level was higher in the EA group: 27.8(1.5) mmol/L in the F group versus 29.1(2) mmol/L in the EA group (P¿=¿0.006). Mean cardiac index (CI) values were 2.6(0.1) L/min/m2 in the F group compared to 2.98(0.09) L/min/m2 in the EA group (P¿=¿0.0081). Length of mechanical ventilation was shorter in the EA group, 5.5(8.8) days compared to the F group, 6.7(5.9) (P¿=¿0.06). Length of Pediatric Cardiac Intensive Care Unit (PCICU) admission was shorter in the EA group: 14(19) days compared to 16(15) in the F group (P¿=¿0.046).ConclusionsIn cardiac surgery infants, EA produced more UO compared to F on POD 0. Generally, less EA dose is required to achieve similar UO than F. EA and F were safe in terms of renal function but EA caused a more intense metabolic alkalosis. EA patients achieved better CI, shorter mechanical ventilation and PCICU admission time.Trial registrationClinicaltrials.gov NCT01628731. Registered 24 June 2012. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 25% |
| United Kingdom | 1 | 25% |
| Unknown | 2 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 2 | 50% |
| Members of the public | 1 | 25% |
| Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 83 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Italy | 1 | 1% |
| Brazil | 1 | 1% |
| Unknown | 81 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 10 | 12% |
| Student > Master | 10 | 12% |
| Student > Bachelor | 10 | 12% |
| Other | 8 | 10% |
| Student > Ph. D. Student | 5 | 6% |
| Other | 15 | 18% |
| Unknown | 25 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 39 | 47% |
| Biochemistry, Genetics and Molecular Biology | 4 | 5% |
| Nursing and Health Professions | 4 | 5% |
| Agricultural and Biological Sciences | 3 | 4% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 2% |
| Other | 4 | 5% |
| Unknown | 27 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 April 2021.
All research outputs
#5,446,994
of 25,374,647 outputs
Outputs from Critical Care
#3,509
of 6,554 outputs
Outputs of similar age
#83,322
of 395,408 outputs
Outputs of similar age from Critical Care
#298
of 466 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,554 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.8. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 395,408 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 466 others from the same source and published within six weeks on either side of this one. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.