Title |
Sustained remission of rheumatoid arthritis with a specific serotonin reuptake inhibitor antidepressant: a case report and review of the literature
|
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Published in |
Journal of Medical Case Reports, March 2011
|
DOI | 10.1186/1752-1947-5-112 |
Pubmed ID | |
Authors |
Rajeev Krishnadas, Ranjit Krishnadas, Jonathan Cavanagh |
Abstract |
The mainstay of pharmacologic therapy for rheumatoid arthritis includes the use of disease-modifying agents like sulfasalazine and methothrexate, and more recently, anti-tumor necrosis factor-α agents. Depression remains a major co-morbidity in patients with rheumatoid arthritis and is thought to contribute to disability and mortality in these patients. Evidence now suggests that a biologic link exists between substrates responsible for inflammatory conditions and mood disorders. Most of this evidence comes from preclinical studies. Nevertheless, more research into this area is helping us to understand the possible mechanisms through which these conditions interact with each other. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 40% |
Unknown | 3 | 60% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 80% |
Scientists | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 1 | 2% |
Unknown | 55 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 14 | 25% |
Researcher | 12 | 21% |
Student > Master | 6 | 11% |
Student > Bachelor | 5 | 9% |
Professor | 4 | 7% |
Other | 9 | 16% |
Unknown | 6 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 21 | 38% |
Agricultural and Biological Sciences | 8 | 14% |
Biochemistry, Genetics and Molecular Biology | 4 | 7% |
Immunology and Microbiology | 3 | 5% |
Psychology | 3 | 5% |
Other | 9 | 16% |
Unknown | 8 | 14% |