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Prevalence of canid herpesvirus-1 infection in stillborn and dead neonatal puppies in Denmark

Overview of attention for article published in Acta Veterinaria Scandinavica, January 2015
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)
  • High Attention Score compared to outputs of the same age and source (87th percentile)

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1 X user
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3 Facebook pages
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1 Wikipedia page
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Title
Prevalence of canid herpesvirus-1 infection in stillborn and dead neonatal puppies in Denmark
Published in
Acta Veterinaria Scandinavica, January 2015
DOI 10.1186/s13028-014-0092-9
Pubmed ID
Authors

Rikke W Larsen, Matti Kiupel, Hans-Jörg Balzer, Jørgen S Agerholm

Abstract

BackgroundCanid herpesvirus-1 (CaHV-1) infection in puppies less than three weeks of age is often reported to be associated with a lethal generalized necrotizing inflammation and since the discovery of the virus in 1965 several reports of neonatal infections have been published. However, the significance of CaHV-1 for peri- and neonatal mortality in puppies remains unclear. Therefore, we examined stillborn and dead neonatal puppies in Denmark to determine the prevalence of infection and further to correlate infection levels with necropsy findings to assess the possible significance of the infection.ResultsFrom a cross-sectional study of 57 dead puppies, 22.8% (n¿=¿13) were confirmed positive for CaHV-1 by real-time polymerase chain reaction (PCR) of tissue pools of lung/liver and/or spleen/kidney. Specimens from PCR positive cases were further investigated by histology and in situ hybridization (ISH). High levels of CaHV-1 DNA were present in only one case in which lesions and ISH staining consistent with CaHV-1 infection were found as well. CaHV-1 concentrations in the other cases were low and a range of lesions not consistent with CaHV-1 were found. Similar, ISH staining was mostly negative in these except for one case with a few positive cells.ConclusionCaHV-1 infection in stillborn and dead neonatal puppies in Denmark seems to be common, but the direct significance for puppy mortality remains unclear as only one of 13 PCR positive puppies (7.7%) had pathognomonic lesions.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 37 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 24%
Student > Doctoral Student 6 16%
Student > Master 6 16%
Student > Bachelor 3 8%
Professor 3 8%
Other 4 11%
Unknown 6 16%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 14 38%
Agricultural and Biological Sciences 6 16%
Medicine and Dentistry 3 8%
Engineering 2 5%
Linguistics 1 3%
Other 5 14%
Unknown 6 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 March 2023.
All research outputs
#5,239,707
of 25,371,288 outputs
Outputs from Acta Veterinaria Scandinavica
#89
of 837 outputs
Outputs of similar age
#68,003
of 358,864 outputs
Outputs of similar age from Acta Veterinaria Scandinavica
#2
of 16 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 837 research outputs from this source. They receive a mean Attention Score of 3.4. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 358,864 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.