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Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancers

Overview of attention for article published in Journal of Hematology & Oncology, February 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (77th percentile)
  • Good Attention Score compared to outputs of the same age and source (73rd percentile)

Mentioned by

twitter
4 tweeters
wikipedia
4 Wikipedia pages

Citations

dimensions_citation
416 Dimensions

Readers on

mendeley
738 Mendeley
citeulike
2 CiteULike
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Title
Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancers
Published in
Journal of Hematology & Oncology, February 2013
DOI 10.1186/1756-8722-6-19
Pubmed ID
Authors

Xinyuan Li, Pu Fang, Jietang Mai, Eric T Choi, Hong Wang, Xiao-feng Yang

Abstract

There are multiple sources of reactive oxygen species (ROS) in the cell. As a major site of ROS production, mitochondria have drawn considerable interest because it was recently discovered that mitochondrial ROS (mtROS) directly stimulate the production of proinflammatory cytokines and pathological conditions as diverse as malignancies, autoimmune diseases, and cardiovascular diseases all share common phenotype of increased mtROS production above basal levels. Several excellent reviews on this topic have been published, but ever-changing new discoveries mandated a more up-to-date and comprehensive review on this topic. Therefore, we update recent understanding of how mitochondria generate and regulate the production of mtROS and the function of mtROS both in physiological and pathological conditions. In addition, we describe newly developed methods to probe or scavenge mtROS and compare these methods in detail. Thorough understanding of this topic and the application of mtROS-targeting drugs in the research is significant towards development of better therapies to combat inflammatory diseases and inflammatory malignancies.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 738 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 7 <1%
United Kingdom 3 <1%
Poland 2 <1%
China 1 <1%
Denmark 1 <1%
Iran, Islamic Republic of 1 <1%
Japan 1 <1%
Greece 1 <1%
Canada 1 <1%
Other 2 <1%
Unknown 718 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 172 23%
Student > Bachelor 144 20%
Student > Master 109 15%
Researcher 81 11%
Student > Doctoral Student 52 7%
Other 86 12%
Unknown 94 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 215 29%
Biochemistry, Genetics and Molecular Biology 183 25%
Medicine and Dentistry 80 11%
Pharmacology, Toxicology and Pharmaceutical Science 29 4%
Chemistry 26 4%
Other 93 13%
Unknown 112 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 June 2021.
All research outputs
#4,810,450
of 19,519,615 outputs
Outputs from Journal of Hematology & Oncology
#251
of 1,008 outputs
Outputs of similar age
#72,676
of 330,725 outputs
Outputs of similar age from Journal of Hematology & Oncology
#17
of 60 outputs
Altmetric has tracked 19,519,615 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,008 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.2. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 330,725 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 60 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.