You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Title |
Outer membrane protein folding from an energy landscape perspective
|
---|---|
Published in |
BMC Biology, December 2017
|
DOI | 10.1186/s12915-017-0464-5 |
Pubmed ID | |
Authors |
Bob Schiffrin, David J. Brockwell, Sheena E. Radford |
Abstract |
The cell envelope is essential for the survival of Gram-negative bacteria. This specialised membrane is densely packed with outer membrane proteins (OMPs), which perform a variety of functions. How OMPs fold into this crowded environment remains an open question. Here, we review current knowledge about OMP folding mechanisms in vitro and discuss how the need to fold to a stable native state has shaped their folding energy landscapes. We also highlight the role of chaperones and the β-barrel assembly machinery (BAM) in assisting OMP folding in vivo and discuss proposed mechanisms by which this fascinating machinery may catalyse OMP folding. |
X Demographics
The data shown below were collected from the profiles of 28 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 7 | 25% |
United States | 6 | 21% |
Australia | 2 | 7% |
Finland | 1 | 4% |
Turkey | 1 | 4% |
Japan | 1 | 4% |
France | 1 | 4% |
Unknown | 9 | 32% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 15 | 54% |
Scientists | 12 | 43% |
Science communicators (journalists, bloggers, editors) | 1 | 4% |
Mendeley readers
The data shown below were compiled from readership statistics for 133 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 133 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 37 | 28% |
Student > Bachelor | 15 | 11% |
Researcher | 13 | 10% |
Student > Master | 9 | 7% |
Student > Doctoral Student | 9 | 7% |
Other | 18 | 14% |
Unknown | 32 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 53 | 40% |
Agricultural and Biological Sciences | 19 | 14% |
Chemistry | 6 | 5% |
Immunology and Microbiology | 4 | 3% |
Physics and Astronomy | 4 | 3% |
Other | 14 | 11% |
Unknown | 33 | 25% |