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Comparison of DNA methylation profiles in human fetal and adult red blood cell progenitors

Overview of attention for article published in Genome Medicine, January 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • Good Attention Score compared to outputs of the same age and source (78th percentile)

Mentioned by

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21 X users
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2 patents

Citations

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79 Dimensions

Readers on

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112 Mendeley
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Title
Comparison of DNA methylation profiles in human fetal and adult red blood cell progenitors
Published in
Genome Medicine, January 2015
DOI 10.1186/s13073-014-0122-2
Pubmed ID
Authors

Samuel Lessard, Mélissa Beaudoin, Karim Benkirane, Guillaume Lettre

Abstract

DNA methylation is an epigenetic modification that plays an important role during mammalian development. Around birth in humans, the main site of red blood cell production moves from the fetal liver to the bone marrow. DNA methylation changes at the β-globin locus and a switch from fetal to adult hemoglobin production characterize this transition. Understanding this globin switch may improve the treatment of patients with sickle cell disease and β-thalassemia, two of the most common Mendelian diseases in the world. The goal of our study was to describe and compare the genome-wide patterns of DNA methylation in fetal and adult human erythroblasts.

X Demographics

X Demographics

The data shown below were collected from the profiles of 21 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 112 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 2 2%
United States 2 2%
Finland 1 <1%
Japan 1 <1%
Spain 1 <1%
Unknown 105 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 22 20%
Researcher 21 19%
Student > Master 14 13%
Student > Bachelor 7 6%
Student > Doctoral Student 6 5%
Other 21 19%
Unknown 21 19%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 40 36%
Agricultural and Biological Sciences 27 24%
Medicine and Dentistry 13 12%
Computer Science 2 2%
Environmental Science 2 2%
Other 7 6%
Unknown 21 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 March 2021.
All research outputs
#2,433,680
of 25,374,647 outputs
Outputs from Genome Medicine
#547
of 1,585 outputs
Outputs of similar age
#33,046
of 359,949 outputs
Outputs of similar age from Genome Medicine
#6
of 28 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,585 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 26.8. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 359,949 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.