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Arsenic exposure is associated with DNA hypermethylation of the tumor suppressor gene p16

Overview of attention for article published in Journal of Occupational Medicine and Toxicology, December 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#30 of 420)
  • High Attention Score compared to outputs of the same age (95th percentile)

Mentioned by

news
3 news outlets
twitter
1 X user

Citations

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25 Dimensions

Readers on

mendeley
22 Mendeley
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Title
Arsenic exposure is associated with DNA hypermethylation of the tumor suppressor gene p16
Published in
Journal of Occupational Medicine and Toxicology, December 2014
DOI 10.1186/s12995-014-0042-5
Pubmed ID
Authors

Guangming Lu, Huiwen Xu, De Chang, Zhenglai Wu, Xiaoyuan Yao, Shiying Zhang, Zhenlong Li, Jieben Bai, Qing Cai, Wen Zhang

Abstract

Occupational and environmental exposure to inorganic arsenic leads to development of cancer and represents a significant health hazard in more than 70 countries. The underlying mechanism for arsenic-induced carcinogenesis remains unclear. Laboratory studies suggest that arsenic is a poor mutagen but may cause epigenetic silencing of key tumor suppressor genes such as p16 through DNA hypermethylation. However, the evidence for an association between human arsenic exposure and abnormal DNA methylation of tumor suppressor genes is lacking.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Malaysia 1 5%
Unknown 21 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 23%
Researcher 4 18%
Student > Master 3 14%
Student > Doctoral Student 2 9%
Professor 1 5%
Other 3 14%
Unknown 4 18%
Readers by discipline Count As %
Environmental Science 3 14%
Pharmacology, Toxicology and Pharmaceutical Science 2 9%
Engineering 2 9%
Medicine and Dentistry 2 9%
Immunology and Microbiology 1 5%
Other 3 14%
Unknown 9 41%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 29. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 September 2023.
All research outputs
#1,333,090
of 25,490,562 outputs
Outputs from Journal of Occupational Medicine and Toxicology
#30
of 420 outputs
Outputs of similar age
#17,500
of 360,594 outputs
Outputs of similar age from Journal of Occupational Medicine and Toxicology
#1
of 4 outputs
Altmetric has tracked 25,490,562 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 420 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.4. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 360,594 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them