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Diagnosis and management of primary ciliary dyskinesia

Overview of attention for article published in Cilia, January 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

news
1 news outlet
twitter
2 tweeters

Citations

dimensions_citation
108 Dimensions

Readers on

mendeley
163 Mendeley
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Title
Diagnosis and management of primary ciliary dyskinesia
Published in
Cilia, January 2015
DOI 10.1186/s13630-014-0011-8
Pubmed ID
Authors

Claudius Werner, Jörg Große Onnebrink, Heymut Omran

Abstract

Primary ciliary dyskinesia (PCD) is a rare autosomal recessive disorder with defective structure and/or function of motile cilia/flagella, causing chronic upper and lower respiratory tract infections, fertility problems, and disorders of organ laterality. Diagnosing PCD requires a combined approach utilizing characteristic phenotypes and complementary methods for detection of defects of ciliary function and ultrastructure, measurement of nasal nitric oxide and genetic testing. Currently, biallelic mutations in 31 different genes have been linked to PCD allowing a genetic diagnosis in approximately ~ 60% of cases. Management includes surveillance of pulmonary function, imaging, and microbiology of upper and lower airways in addition to daily airway clearance and prompt antibiotic treatment of infections. Early referral to specialized centers that use a multidisciplinary approach is likely to improve outcomes. Currently, evidence-based knowledge on PCD care is missing let alone management guidelines. Research and clinical investigators, supported by European and North American patient support groups, have joined forces under the name of BESTCILIA, a European Commission funded consortium dedicated to improve PCD care and knowledge. Core programs of this network include the establishment of an international PCD registry, the generation of disease specific PCD quality of life questionnaires, and the first randomized controlled trial in PCD.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 163 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 <1%
United States 1 <1%
Sweden 1 <1%
Australia 1 <1%
Unknown 159 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 35 21%
Student > Master 23 14%
Student > Doctoral Student 22 13%
Researcher 21 13%
Other 11 7%
Other 29 18%
Unknown 22 13%
Readers by discipline Count As %
Medicine and Dentistry 70 43%
Biochemistry, Genetics and Molecular Biology 27 17%
Agricultural and Biological Sciences 19 12%
Immunology and Microbiology 6 4%
Nursing and Health Professions 4 2%
Other 10 6%
Unknown 27 17%

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 December 2015.
All research outputs
#621,918
of 6,738,406 outputs
Outputs from Cilia
#2
of 60 outputs
Outputs of similar age
#27,657
of 229,679 outputs
Outputs of similar age from Cilia
#1
of 5 outputs
Altmetric has tracked 6,738,406 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 60 research outputs from this source. They receive a mean Attention Score of 2.7. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 229,679 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them