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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Kaolin-induced chronic hydrocephalus accelerates amyloid deposition and vascular disease in transgenic rats expressing high levels of human APP
|
|---|---|
| Published in |
Fluids and Barriers of the CNS, January 2015
|
| DOI | 10.1186/2045-8118-12-2 |
| Pubmed ID | |
| Authors |
Gerald D Silverberg, Miles C Miller, Crissey L Pascale, Ilias N Caralopoulos, Yuksel Agca, Cansu Agca, Edward G Stopa |
| Abstract |
Normal pressure hydrocephalus (NPH) is most common in the elderly and has a high co-morbidity with Alzheimer's disease (AD) and cerebrovascular disease (CVD). To understand the relationship between NPH, AD and CVD, we investigated how chronic hydrocephalus impacts brain amyloid-beta peptide (Aβ) accumulation and vascular pathology in an AD transgenic rodent model. Previously we showed that the altered CSF physiology produced by kaolin-hydrocephalus in older wild-type Sprague-Dawley rats increased Aβ and hyperphosphorylated Tau (Silverberg et. al. Brain Res. 2010, 1317:286-296). We postulated that hydrocephalus would similarly affect an AD rat model. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 3 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 33% |
| Practitioners (doctors, other healthcare professionals) | 1 | 33% |
| Scientists | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 3% |
| Unknown | 30 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 32% |
| Researcher | 4 | 13% |
| Student > Master | 4 | 13% |
| Professor | 3 | 10% |
| Student > Bachelor | 2 | 6% |
| Other | 3 | 10% |
| Unknown | 5 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 11 | 35% |
| Medicine and Dentistry | 8 | 26% |
| Agricultural and Biological Sciences | 4 | 13% |
| Business, Management and Accounting | 1 | 3% |
| Physics and Astronomy | 1 | 3% |
| Other | 0 | 0% |
| Unknown | 6 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 January 2015.
All research outputs
#14,794,387
of 22,778,347 outputs
Outputs from Fluids and Barriers of the CNS
#206
of 361 outputs
Outputs of similar age
#198,232
of 351,991 outputs
Outputs of similar age from Fluids and Barriers of the CNS
#9
of 12 outputs
Altmetric has tracked 22,778,347 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 361 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 351,991 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.