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Mendeley readers
Attention Score in Context
| Title |
Uptake and fate of surface modified silica nanoparticles in head and neck squamous cell carcinoma
|
|---|---|
| Published in |
Journal of Nanobiotechnology, August 2011
|
| DOI | 10.1186/1477-3155-9-32 |
| Pubmed ID | |
| Authors |
Emina Besic Gyenge, Xenia Darphin, Amina Wirth, Uwe Pieles, Heinrich Walt, Marius Bredell, Caroline Maake |
| Abstract |
Head and neck squamous cell carcinoma (HNSCC) is currently the eighth leading cause of cancer death worldwide. The often severe side effects, functional impairments and unfavorable cosmetic outcome of conventional therapies for HNSCC have prompted the quest for novel treatment strategies, including the evaluation of nanotechnology to improve e.g. drug delivery and cancer imaging. Although silica nanoparticles hold great promise for biomedical applications, they have not yet been investigated in the context of HNSCC. In the present in-vitro study we thus analyzed the cytotoxicity, uptake and intracellular fate of 200-300 nm core-shell silica nanoparticles encapsulating fluorescent dye tris(bipyridine)ruthenium(II) dichloride with hydroxyl-, aminopropyl- or PEGylated surface modifications (Ru@SiO2-OH, Ru@SiO2-NH2, Ru@SiO2-PEG) in the human HNSCC cell line UMB-SCC 745. |
Mendeley readers
The data shown below were compiled from readership statistics for 76 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 3% |
| Czechia | 1 | 1% |
| Malaysia | 1 | 1% |
| China | 1 | 1% |
| Poland | 1 | 1% |
| Unknown | 70 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 18 | 24% |
| Researcher | 9 | 12% |
| Other | 7 | 9% |
| Student > Doctoral Student | 7 | 9% |
| Student > Bachelor | 6 | 8% |
| Other | 22 | 29% |
| Unknown | 7 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 20 | 26% |
| Medicine and Dentistry | 11 | 14% |
| Agricultural and Biological Sciences | 10 | 13% |
| Materials Science | 6 | 8% |
| Engineering | 5 | 7% |
| Other | 13 | 17% |
| Unknown | 11 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 January 2015.
All research outputs
#20,251,039
of 22,780,165 outputs
Outputs from Journal of Nanobiotechnology
#1,209
of 1,405 outputs
Outputs of similar age
#111,119
of 120,906 outputs
Outputs of similar age from Journal of Nanobiotechnology
#5
of 5 outputs
Altmetric has tracked 22,780,165 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,405 research outputs from this source. They receive a mean Attention Score of 3.6. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 120,906 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one.