Title |
Globalization, climate change, and transgenerational epigenetic inheritance: will our descendants be at risk?
|
---|---|
Published in |
Clinical Epigenetics, January 2015
|
DOI | 10.1186/s13148-014-0043-3 |
Pubmed ID | |
Authors |
Carlos Guerrero-Bosagna, Per Jensen |
Abstract |
Transgenerational epigenetic inheritance has gained increased attention due to the possibility that exposure to environmental contaminants induce diseases that propagate across generations through epigenomic alterations in gametes. In laboratory animals, exposure to environmental toxicants such as fungicides, pesticides, or plastic compounds has been shown to produce abnormal reproductive or metabolic phenotypes that are transgenerationally transmitted. Human exposures to environmental toxicants have increased due to industrialization and globalization, as well as the incidence of diseases shown to be transgenerationally transmitted in animal models. This new knowledge poses an urgent call to study transgenerational consequences of current human exposures to environmental toxicants. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 2 | 25% |
France | 2 | 25% |
Australia | 1 | 13% |
United States | 1 | 13% |
Unknown | 2 | 25% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 6 | 75% |
Scientists | 2 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 1% |
Mexico | 1 | 1% |
Chile | 1 | 1% |
Unknown | 71 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 13 | 18% |
Student > Bachelor | 10 | 14% |
Researcher | 9 | 12% |
Student > Master | 8 | 11% |
Professor | 6 | 8% |
Other | 13 | 18% |
Unknown | 15 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 23 | 31% |
Biochemistry, Genetics and Molecular Biology | 10 | 14% |
Medicine and Dentistry | 9 | 12% |
Social Sciences | 6 | 8% |
Nursing and Health Professions | 2 | 3% |
Other | 4 | 5% |
Unknown | 20 | 27% |