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Meta-analysis of defunctioning stoma in low anterior resection with total mesorectal excision for rectal cancer: evidence based on thirteen studies

Overview of attention for article published in World Journal of Surgical Oncology, January 2015
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Title
Meta-analysis of defunctioning stoma in low anterior resection with total mesorectal excision for rectal cancer: evidence based on thirteen studies
Published in
World Journal of Surgical Oncology, January 2015
DOI 10.1186/s12957-014-0417-1
Pubmed ID
Authors

Wen-long Gu, Sheng-wen Wu

Abstract

BackgroundRecent studies have shown that a protective stoma can reduce morbidity in low anterior resection for rectal cancer; however, the necessity of it is still controversially discussed.MethodsWe performed this meta-analysis to provide a comprehensive evaluation of the role of defunctioning stoma in low anterior resection for rectal cancer on the rates of anastomotic leakage and reoperation related to leakage with or without defunctioning stoma by calculating the pooled risk ratio.ResultsStudies and relevant literature published between 2004 and 2014 regarding the construction of a protective stoma after low anterior resection were searched though PubMed and EMBASE databases. Finally, a total of 13 studies including 8,002 patients were included in this meta-analysis. The results indicated that protective stomas significantly reduced the rate of postoperative anastomotic leakage and reoperation after low anterior rectal resection. The pooled risk ratios were 0.47 (95% CI: 0.33¿0.68, P <0.0001) and 0.36 (95% CI: 028¿0.46, P <0.00001), respectively.ConclusionsThe findings from this present meta-analysis suggest that a defunctioning stoma could effectively reduce the clinical consequences of anastomotic leakage and reoperation, it is recommended in patients undergoing low rectal anterior resection for rectal cancer.

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Mendeley readers

Mendeley readers

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Geographical breakdown

Country Count As %
Italy 1 1%
Unknown 99 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 14%
Student > Master 14 14%
Student > Bachelor 12 12%
Student > Doctoral Student 12 12%
Other 9 9%
Other 17 17%
Unknown 22 22%
Readers by discipline Count As %
Medicine and Dentistry 58 58%
Nursing and Health Professions 5 5%
Agricultural and Biological Sciences 2 2%
Biochemistry, Genetics and Molecular Biology 2 2%
Psychology 2 2%
Other 5 5%
Unknown 26 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 February 2015.
All research outputs
#20,656,820
of 25,374,647 outputs
Outputs from World Journal of Surgical Oncology
#1,099
of 2,145 outputs
Outputs of similar age
#267,726
of 359,728 outputs
Outputs of similar age from World Journal of Surgical Oncology
#78
of 118 outputs
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We're also able to compare this research output to 118 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.