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Mendeley readers
| Title |
Donor-host mitochondrial compatibility improves efficiency of bovine somatic cell nuclear transfer
|
|---|---|
| Published in |
BMC Developmental Biology, March 2010
|
| DOI | 10.1186/1471-213x-10-31 |
| Pubmed ID | |
| Authors |
Zhong-hai Yan, Yi-ye Zhou, Jing Fu, Fei Jiao, Lei-wen Zhao, Peng-fei Guan, Shu-zhen Huang, Yi-tao Zeng, Fanyi Zeng |
| Abstract |
The interaction between the karyoplast and cytoplast plays an important role in the efficiency of somatic cell nuclear transfer (SCNT), but the underlying mechanism remains unclear. It is generally accepted that in nuclear transfer embryos, the reprogramming of gene expression is induced by epigenetic mechanisms and does not involve modifications of DNA sequences. In cattle, oocytes with various mitochondrial DNA (mtDNA) haplotypes usually have different ATP content and can further affect the efficiency of in vitro production of embryos. As mtDNA comes from the recipient oocyte during SCNT and is regulated by genes in the donor nucleus, it is a perfect model to investigate the interaction between donor nuclei and host oocytes in SCNT. |
Mendeley readers
The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 6% |
| Unknown | 29 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 10 | 32% |
| Student > Bachelor | 4 | 13% |
| Student > Postgraduate | 3 | 10% |
| Student > Master | 3 | 10% |
| Student > Doctoral Student | 2 | 6% |
| Other | 5 | 16% |
| Unknown | 4 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 16 | 52% |
| Biochemistry, Genetics and Molecular Biology | 5 | 16% |
| Medicine and Dentistry | 2 | 6% |
| Immunology and Microbiology | 1 | 3% |
| Veterinary Science and Veterinary Medicine | 1 | 3% |
| Other | 2 | 6% |
| Unknown | 4 | 13% |