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Mendeley readers
Title |
Stress of different types increases the proinflammatory load in rheumatoid arthritis
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Published in |
Arthritis Research & Therapy, June 2009
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DOI | 10.1186/ar2712 |
Pubmed ID | |
Authors |
Rainer H Straub, Joachim R Kalden |
Abstract |
Stress in patients with chronic inflammatory diseases such as rheumatoid arthritis (RA) stimulates proinflammatory mechanisms due to the defect of stress response systems (for example, the sympathetic nervous system and the hypothalamic-pituitary-adrenal axis). Among other mechanisms, the loss of sympathetic nerve fibers in inflamed tissue and inadequate cortisol secretion in relation to inflammation lead to an enhanced proinflammatory load in RA. Stress and the subsequent stimulation of inflammation (systemic and local) lead to increased sensitization of pain and further defects of stress response systems (vicious cycle of stress, pain, and inflammation). |
Mendeley readers
The data shown below were compiled from readership statistics for 66 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Netherlands | 1 | 2% |
Norway | 1 | 2% |
Unknown | 64 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 13 | 20% |
Researcher | 10 | 15% |
Student > Ph. D. Student | 8 | 12% |
Student > Master | 7 | 11% |
Student > Doctoral Student | 6 | 9% |
Other | 10 | 15% |
Unknown | 12 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 22 | 33% |
Agricultural and Biological Sciences | 7 | 11% |
Nursing and Health Professions | 7 | 11% |
Psychology | 4 | 6% |
Neuroscience | 3 | 5% |
Other | 9 | 14% |
Unknown | 14 | 21% |