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Macrophages inhibit human osteosarcoma cell growth after activation with the bacterial cell wall derivative liposomal muramyl tripeptide in combination with interferon-γ

Overview of attention for article published in Journal of Experimental & Clinical Cancer Research, March 2014
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (66th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (55th percentile)

Mentioned by

patent
2 patents
facebook
1 Facebook page

Readers on

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72 Mendeley
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Title
Macrophages inhibit human osteosarcoma cell growth after activation with the bacterial cell wall derivative liposomal muramyl tripeptide in combination with interferon-γ
Published in
Journal of Experimental & Clinical Cancer Research, March 2014
DOI 10.1186/1756-9966-33-27
Pubmed ID
Authors

Jens HW Pahl, Kitty MC Kwappenberg, Eleni M Varypataki, Susy J Santos, Marieke L Kuijjer, Susan Mohamed, Juul T Wijnen, Maarten JD van Tol, Anne-Marie Cleton-Jansen, R Maarten Egeler, Wim Jiskoot, Arjan C Lankester, Marco W Schilham

Abstract

In osteosarcoma, the presence of tumor-infiltrating macrophages positively correlates with patient survival in contrast to the negative effect of tumor-associated macrophages in patients with other tumors. Liposome-encapsulated muramyl tripeptide (L-MTP-PE) has been introduced in the treatment of osteosarcoma patients, which may enhance the potential anti-tumor activity of macrophages. Direct anti-tumor activity of human macrophages against human osteosarcoma cells has not been described so far. Hence, we assessed osteosarcoma cell growth after co-culture with human macrophages.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Germany 1 1%
Unknown 70 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 19%
Student > Ph. D. Student 9 13%
Student > Master 7 10%
Student > Bachelor 7 10%
Student > Doctoral Student 6 8%
Other 17 24%
Unknown 12 17%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 13 18%
Medicine and Dentistry 13 18%
Immunology and Microbiology 10 14%
Agricultural and Biological Sciences 9 13%
Pharmacology, Toxicology and Pharmaceutical Science 5 7%
Other 9 13%
Unknown 13 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 February 2023.
All research outputs
#8,270,860
of 25,394,764 outputs
Outputs from Journal of Experimental & Clinical Cancer Research
#536
of 2,384 outputs
Outputs of similar age
#75,833
of 235,430 outputs
Outputs of similar age from Journal of Experimental & Clinical Cancer Research
#4
of 9 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. This one has received more attention than most of these and is in the 66th percentile.
So far Altmetric has tracked 2,384 research outputs from this source. They receive a mean Attention Score of 4.8. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 235,430 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.