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Mendeley readers
Attention Score in Context
| Title |
Retrograde transport pathways utilised by viruses and protein toxins
|
|---|---|
| Published in |
Virology Journal, April 2006
|
| DOI | 10.1186/1743-422x-3-26 |
| Pubmed ID | |
| Authors |
Robert A Spooner, Daniel C Smith, Andrew J Easton, Lynne M Roberts, Michael J Lord |
| Abstract |
A model has been presented for retrograde transport of certain toxins and viruses from the cell surface to the ER that suggests an obligatory interaction with a glycolipid receptor at the cell surface. Here we review studies on the ER trafficking cholera toxin, Shiga and Shiga-like toxins, Pseudomonas exotoxin A and ricin, and compare the retrograde routes followed by these protein toxins to those of the ER trafficking SV40 and polyoma viruses. We conclude that there is in fact no obligatory requirement for a glycolipid receptor, nor even with a protein receptor in a lipid-rich environment. Emerging data suggests instead that there is no common pathway utilised for retrograde transport by all of these pathogens, the choice of route being determined by the particular receptor utilised. |
Mendeley readers
The data shown below were compiled from readership statistics for 101 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 3% |
| Poland | 1 | <1% |
| Germany | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 95 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 22 | 22% |
| Researcher | 22 | 22% |
| Student > Bachelor | 12 | 12% |
| Professor > Associate Professor | 9 | 9% |
| Student > Master | 7 | 7% |
| Other | 13 | 13% |
| Unknown | 16 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 42 | 42% |
| Biochemistry, Genetics and Molecular Biology | 17 | 17% |
| Medicine and Dentistry | 7 | 7% |
| Immunology and Microbiology | 7 | 7% |
| Chemistry | 6 | 6% |
| Other | 9 | 9% |
| Unknown | 13 | 13% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 January 2024.
All research outputs
#7,451,942
of 22,782,096 outputs
Outputs from Virology Journal
#898
of 3,042 outputs
Outputs of similar age
#23,299
of 66,316 outputs
Outputs of similar age from Virology Journal
#2
of 6 outputs
Altmetric has tracked 22,782,096 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,042 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.7. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 66,316 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.