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Analysis of gene expression profiles in HeLa cells in response to overexpression or siRNA-mediated depletion of NASP

Overview of attention for article published in Reproductive Biology and Endocrinology, May 2009
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Title
Analysis of gene expression profiles in HeLa cells in response to overexpression or siRNA-mediated depletion of NASP
Published in
Reproductive Biology and Endocrinology, May 2009
DOI 10.1186/1477-7827-7-45
Pubmed ID
Authors

Oleg M Alekseev, Richard T Richardson, Oleg Alekseev, Michael G O'Rand

Abstract

NASP (Nuclear Autoantigenic Sperm Protein) is a linker histone chaperone required for normal cell division. Changes in NASP expression significantly affect cell growth and development; loss of gene function results in embryonic lethality. However, the mechanism by which NASP exerts its effects in the cell cycle is not understood. To understand the pathways and networks that may involve NASP function, we evaluated gene expression in HeLa cells in which NASP was either overexpressed or depleted by siRNA.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 2%
Chile 1 2%
Brazil 1 2%
Canada 1 2%
Spain 1 2%
United States 1 2%
Unknown 58 91%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 19%
Student > Master 11 17%
Researcher 9 14%
Student > Bachelor 8 13%
Student > Doctoral Student 4 6%
Other 11 17%
Unknown 9 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 22 34%
Biochemistry, Genetics and Molecular Biology 13 20%
Medicine and Dentistry 7 11%
Chemistry 3 5%
Computer Science 2 3%
Other 6 9%
Unknown 11 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 April 2024.
All research outputs
#7,451,942
of 22,782,096 outputs
Outputs from Reproductive Biology and Endocrinology
#283
of 973 outputs
Outputs of similar age
#32,645
of 92,352 outputs
Outputs of similar age from Reproductive Biology and Endocrinology
#4
of 12 outputs
Altmetric has tracked 22,782,096 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 973 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.9. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 92,352 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 19th percentile – i.e., 19% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.