Title |
Diagnosis, treatment, and response assessment in solitary plasmacytoma: updated recommendations from a European Expert Panel
|
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Published in |
Journal of Hematology & Oncology, January 2018
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DOI | 10.1186/s13045-017-0549-1 |
Pubmed ID | |
Authors |
J. Caers, B. Paiva, E. Zamagni, X. Leleu, J. Bladé, S. Y. Kristinsson, C. Touzeau, N. Abildgaard, E. Terpos, R. Heusschen, E. Ocio, M. Delforge, O. Sezer, M. Beksac, H. Ludwig, G. Merlini, P. Moreau, S. Zweegman, M. Engelhardt, L. Rosiñol |
Abstract |
Solitary plasmacytoma is an infrequent form of plasma cell dyscrasia that presents as a single mass of monoclonal plasma cells, located either extramedullary or intraosseous. In some patients, a bone marrow aspiration can detect a low monoclonal plasma cell infiltration which indicates a high risk of early progression to an overt myeloma disease. Before treatment initiation, whole body positron emission tomography-computed tomography or magnetic resonance imaging should be performed to exclude the presence of additional malignant lesions. For decades, treatment has been based on high-dose radiation, but studies exploring the potential benefit of systemic therapies for high-risk patients are urgently needed. In this review, a panel of expert European hematologists updates the recommendations on the diagnosis and management of patients with solitary plasmacytoma. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 216 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 37 | 17% |
Researcher | 26 | 12% |
Student > Postgraduate | 23 | 11% |
Student > Master | 14 | 6% |
Student > Doctoral Student | 12 | 6% |
Other | 37 | 17% |
Unknown | 67 | 31% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 116 | 54% |
Biochemistry, Genetics and Molecular Biology | 7 | 3% |
Nursing and Health Professions | 5 | 2% |
Agricultural and Biological Sciences | 3 | 1% |
Unspecified | 3 | 1% |
Other | 9 | 4% |
Unknown | 73 | 34% |