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Chronic airflow obstruction in Tanzania – a cross-sectional study

Overview of attention for article published in BMC Pulmonary Medicine, January 2018
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Title
Chronic airflow obstruction in Tanzania – a cross-sectional study
Published in
BMC Pulmonary Medicine, January 2018
DOI 10.1186/s12890-018-0577-9
Pubmed ID
Authors

Thomas Zoller, Elirehema H. Mfinanga, Tresphory B. Zumba, Peter J. Asilia, Edwin M. Mutabazi, David Wimmersberger, Florian Kurth, Francis Mhimbira, Frederick Haraka, Klaus Reither

Abstract

Chronic obstructive pulmonary disease is a global problem and available data from sub-Saharan Africa is very limited. A cross-sectional facility-based pilot study among patients and visitors to an urban and a rural primary healthcare facility was conducted in coastal Tanzania. The primary outcome was the prevalence of chronic airflow obstruction. The final analysis included 598 participants with valid post-bronchodilator spirometry. Applying ATS/ERS spirometric criteria, chronic airflow obstruction was found in n = 24 (4%, CI95 2.7-5.9) participants and in n = 30 (5%, CI95 3.5-7.1) applying GOLD spirometric criteria. To analyse risk factors for chronic airflow obstruction including those not meeting ATS/ERS or GOLD criteria, FEF25-75 and FEV1% predicted was analysed in participants without evidence of pulmonary restriction among those exposed or not exposed to risk factors (n = 552). FEV1% predicted, but in particular FEF25-75 decreased with increasing symptom severity of shortness of breath as well as limitations in daily activities of participants. Cooking in general and cooking with biomass fuels vs. gas or electricity was associated with significantly lower FEF25-75, but not with lower FEV1% predicted. Participants having refrained from taking a job because of shortness of breath exhibited lower FEF25-75 (p < 0.01). A history of prior active TB was the most relevant risk factor associated with a decrease in FEF25-75 as well as FEV1% predicted. This study demonstrated a relevant prevalence of chronic airflow obstruction in primary healthcare attendants and healthy visitors of a Tanzanian hospital. Using the baseline data provided, larger and population-based studies are needed to validate these findings. TB may have more impact on development of chronic airway obstruction than smoking in Africa. Due to the influence of age on the GOLD definition of chronic airflow obstruction, studies should report results using both ATS/ERS and GOLD definitions and include age-stratified analysis. Analysis of FEV1 and in particular FEF25-75 may yield additional information on risk factors and earlier stages of chronic airflow obstruction.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 70 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 70 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 11 16%
Researcher 9 13%
Student > Ph. D. Student 6 9%
Student > Bachelor 6 9%
Student > Doctoral Student 5 7%
Other 14 20%
Unknown 19 27%
Readers by discipline Count As %
Medicine and Dentistry 19 27%
Nursing and Health Professions 10 14%
Unspecified 4 6%
Environmental Science 2 3%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Other 11 16%
Unknown 22 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 January 2018.
All research outputs
#20,459,801
of 23,016,919 outputs
Outputs from BMC Pulmonary Medicine
#1,608
of 1,950 outputs
Outputs of similar age
#378,310
of 441,339 outputs
Outputs of similar age from BMC Pulmonary Medicine
#72
of 84 outputs
Altmetric has tracked 23,016,919 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,950 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 441,339 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 84 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.