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The tyranny of adenosine recognition among RNA aptamers to coenzyme A

Overview of attention for article published in BMC Ecology and Evolution, December 2003
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3 Wikipedia pages

Citations

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27 Dimensions

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Title
The tyranny of adenosine recognition among RNA aptamers to coenzyme A
Published in
BMC Ecology and Evolution, December 2003
DOI 10.1186/1471-2148-3-26
Pubmed ID
Authors

Dayal Saran, Joseph Frank, Donald H Burke

Abstract

Understanding the diversity of interactions between RNA aptamers and nucleotide cofactors promises both to facilitate the design of new RNA enzymes that utilize these cofactors and to constrain models of RNA World evolution. In previous work, we isolated six pools of high affinity RNA aptamers to coenzyme A (CoA), the principle cofactor in biological acyltransfer reactions. Interpretation of the evolutionary significance of those results was made difficult by the fact that the affinity resin attachment strongly influenced the outcome of those selections. Here we describe the selection of four new pools isolated on a disulfide-linked CoA affinity matrix to minimize context-dependent recognition imposed by the attachment to the solid support.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 3%
China 1 3%
Unknown 37 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 28%
Student > Ph. D. Student 7 18%
Student > Postgraduate 3 8%
Professor > Associate Professor 3 8%
Student > Master 3 8%
Other 8 21%
Unknown 4 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 19 49%
Chemistry 8 21%
Biochemistry, Genetics and Molecular Biology 2 5%
Medicine and Dentistry 2 5%
Psychology 1 3%
Other 1 3%
Unknown 6 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 April 2024.
All research outputs
#8,534,528
of 25,371,288 outputs
Outputs from BMC Ecology and Evolution
#1,997
of 3,714 outputs
Outputs of similar age
#36,271
of 143,198 outputs
Outputs of similar age from BMC Ecology and Evolution
#6
of 8 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,714 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.5. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 143,198 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.