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Crystal structures of a purple acid phosphatase, representing different steps of this enzyme's catalytic cycle

Overview of attention for article published in BMC Molecular and Cell Biology, January 2008
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Title
Crystal structures of a purple acid phosphatase, representing different steps of this enzyme's catalytic cycle
Published in
BMC Molecular and Cell Biology, January 2008
DOI 10.1186/1472-6807-8-6
Pubmed ID
Authors

Gerhard Schenk, Tristan W Elliott, Eleanor Leung, Lyle E Carrington, Nataša Mitić, Lawrence R Gahan, Luke W Guddat

Abstract

Purple acid phosphatases belong to the family of binuclear metallohydrolases and are involved in a multitude of biological functions, ranging from bacterial killing and bone metabolism in animals to phosphate uptake in plants. Due to its role in bone resorption purple acid phosphatase has evolved into a promising target for the development of anti-osteoporotic chemotherapeutics. The design of specific and potent inhibitors for this enzyme is aided by detailed knowledge of its reaction mechanism. However, despite considerable effort in the last 10 years various aspects of the basic molecular mechanism of action are still not fully understood.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
India 1 1%
Germany 1 1%
Unknown 69 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 25%
Student > Bachelor 14 19%
Researcher 8 11%
Professor 5 7%
Student > Master 5 7%
Other 13 18%
Unknown 9 13%
Readers by discipline Count As %
Chemistry 23 32%
Agricultural and Biological Sciences 21 29%
Biochemistry, Genetics and Molecular Biology 10 14%
Nursing and Health Professions 2 3%
Environmental Science 1 1%
Other 3 4%
Unknown 12 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 August 2021.
All research outputs
#8,534,976
of 25,373,627 outputs
Outputs from BMC Molecular and Cell Biology
#334
of 1,233 outputs
Outputs of similar age
#46,627
of 172,057 outputs
Outputs of similar age from BMC Molecular and Cell Biology
#2
of 11 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,233 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 172,057 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.