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Comparative genomics analysis of triatomines reveals common first line and inducible immunity-related genes and the absence of Imd canonical components among hemimetabolous arthropods

Overview of attention for article published in Parasites & Vectors, January 2018
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Title
Comparative genomics analysis of triatomines reveals common first line and inducible immunity-related genes and the absence of Imd canonical components among hemimetabolous arthropods
Published in
Parasites & Vectors, January 2018
DOI 10.1186/s13071-017-2561-2
Pubmed ID
Authors

Federico Alonso Zumaya-Estrada, Jesús Martínez-Barnetche, Andrés Lavore, Rolando Rivera-Pomar, Mario Henry Rodríguez

Abstract

Insects operate complex humoral and cellular immune strategies to fend against invading microorganisms. The majority of these have been characterized in Drosophila and other dipterans. Information on hemipterans, including Triatominae vectors of Chagas disease remains incomplete and fractionated. We identified putative immune-related homologs of three Triatominae vectors of Chagas disease, Triatoma pallidipennis, T. dimidiata and T. infestans (TTTs), using comparative transcriptomics based on established immune response gene references, in conjunction with the predicted proteomes of Rhodnius prolixus, Cimex lecticularis and Acyrthosiphon pisum hemimetabolous. We present a compressive description of the humoral and cellular innate immune components of these TTTs and extend the immune information of other related hemipterans. Key homologs of the constitutive and induced immunity genes were identified in all the studied hemipterans. Our results in the TTTs extend previous observations in other hemipterans lacking several components of the Imd signaling pathway. Comparison with other hexapods, using published data, revealed that the absence of various Imd canonical components is common in several hemimetabolous species.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 47 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 9 19%
Researcher 6 13%
Student > Postgraduate 4 9%
Student > Doctoral Student 3 6%
Professor 3 6%
Other 10 21%
Unknown 12 26%
Readers by discipline Count As %
Agricultural and Biological Sciences 13 28%
Biochemistry, Genetics and Molecular Biology 8 17%
Immunology and Microbiology 4 9%
Chemistry 2 4%
Medicine and Dentistry 2 4%
Other 3 6%
Unknown 15 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 August 2018.
All research outputs
#14,287,326
of 23,342,232 outputs
Outputs from Parasites & Vectors
#2,705
of 5,557 outputs
Outputs of similar age
#234,790
of 442,853 outputs
Outputs of similar age from Parasites & Vectors
#79
of 149 outputs
Altmetric has tracked 23,342,232 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,557 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 442,853 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 149 others from the same source and published within six weeks on either side of this one. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.