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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Role of TNFα in pulmonary pathophysiology
|
|---|---|
| Published in |
Respiratory Research, October 2006
|
| DOI | 10.1186/1465-9921-7-125 |
| Pubmed ID | |
| Authors |
Srirupa Mukhopadhyay, John R Hoidal, Tapan K Mukherjee |
| Abstract |
Tumor necrosis factor alpha (TNFalpha) is the most widely studied pleiotropic cytokine of the TNF superfamily. In pathophysiological conditions, generation of TNFalpha at high levels leads to the development of inflammatory responses that are hallmarks of many diseases. Of the various pulmonary diseases, TNFalpha is implicated in asthma, chronic bronchitis (CB), chronic obstructive pulmonary disease (COPD), acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). In addition to its underlying role in the inflammatory events, there is increasing evidence for involvement of TNFalpha in the cytotoxicity. Thus, pharmacological agents that can either suppress the production of TNFalpha or block its biological actions may have potential therapeutic value against a wide variety of diseases. Despite some immunological side effects, anti-TNFalpha therapeutic strategies represent an important breakthrough in the treatment of inflammatory diseases and may have a role in pulmonary diseases characterized by inflammation and cell death. |
X Demographics
The data shown below were collected from the profiles of 12 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 42% |
| Belgium | 1 | 8% |
| Unknown | 6 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 10 | 83% |
| Practitioners (doctors, other healthcare professionals) | 1 | 8% |
| Scientists | 1 | 8% |
Mendeley readers
The data shown below were compiled from readership statistics for 280 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 3 | 1% |
| United States | 3 | 1% |
| India | 1 | <1% |
| Japan | 1 | <1% |
| Uruguay | 1 | <1% |
| Unknown | 271 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 65 | 23% |
| Researcher | 40 | 14% |
| Student > Master | 25 | 9% |
| Student > Bachelor | 24 | 9% |
| Student > Postgraduate | 20 | 7% |
| Other | 48 | 17% |
| Unknown | 58 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 66 | 24% |
| Agricultural and Biological Sciences | 44 | 16% |
| Biochemistry, Genetics and Molecular Biology | 25 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 18 | 6% |
| Immunology and Microbiology | 17 | 6% |
| Other | 38 | 14% |
| Unknown | 72 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 April 2024.
All research outputs
#4,334,284
of 25,800,372 outputs
Outputs from Respiratory Research
#549
of 3,114 outputs
Outputs of similar age
#12,338
of 84,485 outputs
Outputs of similar age from Respiratory Research
#2
of 7 outputs
Altmetric has tracked 25,800,372 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,114 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.9. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 84,485 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.