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Mendeley readers
Attention Score in Context
| Title |
Sirtuins: Sir2-related NAD-dependent protein deacetylases
|
|---|---|
| Published in |
Genome Biology, April 2004
|
| DOI | 10.1186/gb-2004-5-5-224 |
| Pubmed ID | |
| Authors |
Brian J North, Eric Verdin |
| Abstract |
Silent information regulator 2 (Sir2) proteins, or sirtuins, are protein deacetylases dependent on nicotine adenine dinucleotide (NAD) and are found in organisms ranging from bacteria to humans. In eukaryotes, sirtuins regulate transcriptional repression, recombination, the cell-division cycle, microtubule organization, and cellular responses to DNA-damaging agents. Sirtuins have also been implicated in regulating the molecular mechanisms of aging. The Sir2 catalytic domain, which is shared among all sirtuins, consists of two distinct domains that bind NAD and the acetyl-lysine substrate, respectively. In addition to the catalytic domain, eukaryotic sirtuins contain variable amino- and carboxy-terminal extensions that regulate their subcellular localizations and catalytic activity. |
Mendeley readers
The data shown below were compiled from readership statistics for 370 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 1% |
| Germany | 2 | <1% |
| Portugal | 2 | <1% |
| Belgium | 2 | <1% |
| France | 2 | <1% |
| Italy | 2 | <1% |
| Austria | 1 | <1% |
| Netherlands | 1 | <1% |
| United Kingdom | 1 | <1% |
| Other | 3 | <1% |
| Unknown | 349 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 98 | 26% |
| Student > Master | 55 | 15% |
| Student > Bachelor | 44 | 12% |
| Researcher | 43 | 12% |
| Professor > Associate Professor | 25 | 7% |
| Other | 54 | 15% |
| Unknown | 51 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 144 | 39% |
| Biochemistry, Genetics and Molecular Biology | 77 | 21% |
| Chemistry | 26 | 7% |
| Medicine and Dentistry | 25 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 14 | 4% |
| Other | 21 | 6% |
| Unknown | 63 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 May 2020.
All research outputs
#8,535,684
of 25,374,917 outputs
Outputs from Genome Biology
#3,489
of 4,467 outputs
Outputs of similar age
#20,950
of 62,248 outputs
Outputs of similar age from Genome Biology
#8
of 16 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one is in the 14th percentile – i.e., 14% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 62,248 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.