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mRNA export in the apicomplexan parasite Toxoplasma gondii: emerging divergent components of a crucial pathway

Overview of attention for article published in Parasites & Vectors, January 2018
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  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (98th percentile)

Mentioned by

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65 X users

Citations

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26 Mendeley
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Title
mRNA export in the apicomplexan parasite Toxoplasma gondii: emerging divergent components of a crucial pathway
Published in
Parasites & Vectors, January 2018
DOI 10.1186/s13071-018-2648-4
Pubmed ID
Authors

Andréa Rodrigues Ávila, Alexjandro Cabezas-Cruz, Mathieu Gissot

Abstract

Control of gene expression is crucial for parasite survival and is the result of a series of processes that are regulated to permit fine-tuning of gene expression in response to biological changes during the life-cycle of apicomplexan parasites. Control of mRNA nuclear export is a key process in eukaryotic cells but is poorly understood in apicomplexan parasites. Here, we review recent knowledge regarding this process with an emphasis on T. gondii. We describe the presence of divergent orthologs and discuss structural and functional differences in export factors between apicomplexans and other eukaryotic lineages. Undoubtedly, the use of the CRISPR/Cas9 system in high throughput screenings associated with the discovery of mRNA nuclear export complexes by proteomic analysis will contribute to identify these divergent factors. Ligand-based or structure-based strategies may be applied to investigate the potential use of these proteins as targets for new antiprotozoal agents.

X Demographics

X Demographics

The data shown below were collected from the profiles of 65 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 26 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 35%
Researcher 7 27%
Student > Bachelor 1 4%
Student > Master 1 4%
Unknown 8 31%
Readers by discipline Count As %
Agricultural and Biological Sciences 5 19%
Immunology and Microbiology 4 15%
Biochemistry, Genetics and Molecular Biology 3 12%
Veterinary Science and Veterinary Medicine 2 8%
Medicine and Dentistry 2 8%
Other 1 4%
Unknown 9 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 50. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 August 2023.
All research outputs
#857,797
of 25,816,430 outputs
Outputs from Parasites & Vectors
#99
of 6,082 outputs
Outputs of similar age
#19,822
of 453,231 outputs
Outputs of similar age from Parasites & Vectors
#3
of 153 outputs
Altmetric has tracked 25,816,430 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,082 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 453,231 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 153 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.