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Mendeley readers
Attention Score in Context
| Title |
In vivo antimuscarinic actions of the third generation antihistaminergic agent, desloratadine
|
|---|---|
| Published in |
BMC Pharmacology, August 2005
|
| DOI | 10.1186/1471-2210-5-13 |
| Pubmed ID | |
| Authors |
G Howell, L West, C Jenkins, B Lineberry, D Yokum, R Rockhold |
| Abstract |
Muscarinic receptor mediated adverse effects, such as sedation and xerostomia, significantly hinder the therapeutic usefulness of first generation antihistamines. Therefore, second and third generation antihistamines which effectively antagonize the H1 receptor without significant affinity for muscarinic receptors have been developed. However, both in vitro and in vivo experimentation indicates that the third generation antihistamine, desloratadine, antagonizes muscarinic receptors. To fully examine the in vivo antimuscarinic efficacy of desloratadine, two murine and two rat models were utilized. The murine models sought to determine the efficacy of desloratadine to antagonize muscarinic agonist induced salivation, lacrimation, and tremor. Desloratadine's effect on the cardiovascular system was explored in both rodent models. |
Mendeley readers
The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Austria | 1 | 4% |
| Unknown | 24 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 7 | 28% |
| Student > Ph. D. Student | 4 | 16% |
| Researcher | 3 | 12% |
| Other | 2 | 8% |
| Professor > Associate Professor | 2 | 8% |
| Other | 5 | 20% |
| Unknown | 2 | 8% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 13 | 52% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 12% |
| Arts and Humanities | 1 | 4% |
| Biochemistry, Genetics and Molecular Biology | 1 | 4% |
| Veterinary Science and Veterinary Medicine | 1 | 4% |
| Other | 4 | 16% |
| Unknown | 2 | 8% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 January 2022.
All research outputs
#7,527,793
of 22,971,207 outputs
Outputs from BMC Pharmacology
#26
of 63 outputs
Outputs of similar age
#20,369
of 58,230 outputs
Outputs of similar age from BMC Pharmacology
#1
of 1 outputs
Altmetric has tracked 22,971,207 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 63 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 58,230 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them