Title |
Single bolus versus split dose gadolinium administration in extra-cellular volume calculation at 3 Tesla
|
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Published in |
Critical Reviews in Diagnostic Imaging, January 2015
|
DOI | 10.1186/s12968-015-0112-6 |
Pubmed ID | |
Authors |
Adam K McDiarmid, Peter P Swoboda, Bara Erhayiem, David P Ripley, Ananth Kidambi, David A Broadbent, David M Higgins, John P Greenwood, Sven Plein |
Abstract |
Diffuse myocardial fibrosis may be quantified with cardiovascular magnetic resonance (CMR) by calculating extra-cellular volume (ECV) from native and post-contrast T1 values. Accurate ECV calculation is dependent upon the contrast agent having reached equilibrium within tissue compartments. Previous studies have used infusion or single bolus injections of contrast to calculate ECV. In clinical practice however, split dose contrast injection is commonly used as part of stress/rest perfusion studies. In this study we sought to assess the effects of split dose versus single bolus contrast administration on ECV calculation. |
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