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Full genome characterization of porcine circovirus type 3 isolates reveals the existence of two distinct groups of virus strains

Overview of attention for article published in Virology Journal, January 2018
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  • Above-average Attention Score compared to outputs of the same age (61st percentile)

Mentioned by

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5 tweeters

Citations

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59 Dimensions

Readers on

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44 Mendeley
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Title
Full genome characterization of porcine circovirus type 3 isolates reveals the existence of two distinct groups of virus strains
Published in
Virology Journal, January 2018
DOI 10.1186/s12985-018-0929-3
Pubmed ID
Authors

Robert Fux, Christina Söckler, Ellen Kathrin Link, Christine Renken, Roman Krejci, Gerd Sutter, Mathias Ritzmann, Matthias Eddicks

Abstract

The occurrence of the novel porcine circovirus type 3 (PCV3) was reported from the Americas, Asia and Europe. Although this virus was detected in association with various clinical syndromes in pigs, its role as possible swine pathogen remains unclear. PCV3 was detected with high prevalence in Polish farms, but to date no genome sequences were available from European PCV3 strains. We collected 1060 serum samples from piglets at the age of 20-24 weeks from 53 farms distributed all over Germany. PCV3 DNA was detected using a real-time PCR and subsequently complete PCV3 genome sequences were obtained after multiply primed rolling circle amplification and sequencing of overlapping PCR products. Phylogenetic analysis was performed by neighbor-joining method and maximum likelihood method. We obtained 15 complete PCV3 genome sequences as well as nine partial sequences including the putative ORFs 1, 2 and 3 from PCV3 viremic animals in German pig farms. Phylogenetic analysis of these German as well as 30 full genome sequences received from GenBank divided the PCV3 strains into two main groups and several subclusters. Furthermore, we were able to define group specific amino acid patterns in open reading frame 1 and 2. PCV3 is distributed with high prevalence in German pig industry. Phylogenetic analysis revealed two clearly separated groups of PCV3 strains, which might be considered as PCV3 genotypes. Specific nucleotide and amino acid marker positions may serve for easy and fast intraspecies classification and genotyping of PCV3 strains. No correlation between PCV3 variants with their geographical origin was evident. We found the same diversity of PCV3 strains in Germany as in other countries. We hypothesize that PCV3 is not a newly emerging virus in the German pig population. Future studies will have to show, if PCV3 genotype specific biological properties are evident.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 44 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 20%
Researcher 9 20%
Student > Doctoral Student 6 14%
Student > Master 4 9%
Student > Bachelor 4 9%
Other 4 9%
Unknown 8 18%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 18 41%
Agricultural and Biological Sciences 8 18%
Biochemistry, Genetics and Molecular Biology 7 16%
Engineering 2 5%
Unknown 9 20%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 September 2018.
All research outputs
#6,999,644
of 13,810,416 outputs
Outputs from Virology Journal
#739
of 2,220 outputs
Outputs of similar age
#134,418
of 356,160 outputs
Outputs of similar age from Virology Journal
#1
of 1 outputs
Altmetric has tracked 13,810,416 research outputs across all sources so far. This one is in the 48th percentile – i.e., 48% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,220 research outputs from this source. They receive a mean Attention Score of 3.5. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 356,160 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them