Title |
The transferome of metabolic genes explored: analysis of the horizontal transfer of enzyme encoding genes in unicellular eukaryotes
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Published in |
Genome Biology, April 2009
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DOI | 10.1186/gb-2009-10-4-r36 |
Pubmed ID | |
Authors |
John W Whitaker, Glenn A McConkey, David R Westhead |
Abstract |
Metabolic networks are responsible for many essential cellular processes, and exhibit a high level of evolutionary conservation from bacteria to eukaryotes. If genes encoding metabolic enzymes are horizontally transferred and are advantageous, they are likely to become fixed. Horizontal gene transfer (HGT) has played a key role in prokaryotic evolution and its importance in eukaryotes is increasingly evident. High levels of endosymbiotic gene transfer (EGT) accompanied the establishment of plastids and mitochondria, and more recent events have allowed further acquisition of bacterial genes. Here, we present the first comprehensive multi-species analysis of E/HGT of genes encoding metabolic enzymes from bacteria to unicellular eukaryotes. |
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Demographic breakdown
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Scientists | 1 | 100% |
Mendeley readers
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India | 1 | <1% |
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Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 31 | 25% |
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Student > Bachelor | 13 | 11% |
Professor > Associate Professor | 10 | 8% |
Student > Master | 10 | 8% |
Other | 24 | 20% |
Unknown | 7 | 6% |
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Immunology and Microbiology | 4 | 3% |
Chemistry | 3 | 2% |
Other | 6 | 5% |
Unknown | 9 | 7% |