Title |
Total and functional parasite specific IgE responses in Plasmodium falciparum-infected patients exhibiting different clinical status
|
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Published in |
Malaria Journal, January 2007
|
DOI | 10.1186/1475-2875-6-1 |
Pubmed ID | |
Authors |
Joana Duarte, Prakash Deshpande, Vincent Guiyedi, Salah Mécheri, Constantin Fesel, Pierre-André Cazenave, Gyan C Mishra, Maryvonne Kombila, Sylviane Pied |
Abstract |
There is an increase of serum levels of IgE during Plasmodium falciparum infections in individuals living in endemic areas. These IgEs either protect against malaria or increase malaria pathogenesis. To get an insight into the exact role played by IgE in the outcome of P. falciparum infection, total IgE levels and functional anti-parasite IgE response were studied in children and adults, from two different endemic areas Gabon and India, exhibiting either uncomplicated malaria, severe non cerebral malaria or cerebral malaria, in comparison with control individuals. |
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Geographical breakdown
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United Kingdom | 2 | 2% |
Netherlands | 1 | 1% |
Indonesia | 1 | 1% |
Sweden | 1 | 1% |
Colombia | 1 | 1% |
India | 1 | 1% |
Taiwan | 1 | 1% |
Unknown | 88 | 89% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 25 | 25% |
Student > Ph. D. Student | 18 | 18% |
Student > Master | 13 | 13% |
Student > Bachelor | 8 | 8% |
Professor | 7 | 7% |
Other | 15 | 15% |
Unknown | 13 | 13% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 18 | 18% |
Immunology and Microbiology | 13 | 13% |
Biochemistry, Genetics and Molecular Biology | 9 | 9% |
Computer Science | 1 | 1% |
Other | 9 | 9% |
Unknown | 15 | 15% |