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Toxicity of polymyxins: a systematic review of the evidence from old and recent studies

Overview of attention for article published in Critical Care, February 2006
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (87th percentile)

Mentioned by

news
1 news outlet
twitter
3 X users
wikipedia
9 Wikipedia pages

Citations

dimensions_citation
637 Dimensions

Readers on

mendeley
576 Mendeley
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Title
Toxicity of polymyxins: a systematic review of the evidence from old and recent studies
Published in
Critical Care, February 2006
DOI 10.1186/cc3995
Pubmed ID
Authors

Matthew E Falagas, Sofia K Kasiakou

Abstract

The increasing problem of multidrug-resistant gram-negative bacteria causing severe infections and the shortage of new antibiotics to combat them has led to the re-evaluation of polymyxins. These antibiotics were discovered from different species of Bacillus polymyxa in 1947; only two of them, polymyxin B and E (colistin), have been used in clinical practice. Their effectiveness in the treatment of infections due to susceptible gram-negative bacteria, including Pseudomonas aeruginosa and Acinetobacter baumannii, has not been generally questioned. However, their use was abandoned, except in patients with cystic fibrosis, because of concerns related to toxicity.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 576 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 5 <1%
Brazil 4 <1%
United Kingdom 3 <1%
Japan 2 <1%
Netherlands 1 <1%
Germany 1 <1%
Australia 1 <1%
Malaysia 1 <1%
Indonesia 1 <1%
Other 4 <1%
Unknown 553 96%

Demographic breakdown

Readers by professional status Count As %
Student > Master 86 15%
Student > Ph. D. Student 74 13%
Researcher 72 13%
Student > Bachelor 69 12%
Other 43 7%
Other 102 18%
Unknown 130 23%
Readers by discipline Count As %
Medicine and Dentistry 135 23%
Agricultural and Biological Sciences 75 13%
Biochemistry, Genetics and Molecular Biology 65 11%
Pharmacology, Toxicology and Pharmaceutical Science 51 9%
Chemistry 32 6%
Other 72 13%
Unknown 146 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 November 2022.
All research outputs
#2,579,140
of 25,728,855 outputs
Outputs from Critical Care
#2,219
of 6,613 outputs
Outputs of similar age
#8,104
of 176,698 outputs
Outputs of similar age from Critical Care
#5
of 41 outputs
Altmetric has tracked 25,728,855 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,613 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.7. This one has gotten more attention than average, scoring higher than 66% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 176,698 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 41 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.