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The expression and significance of insulin-like growth factor-1 receptor and its pathway on breast cancer stem/progenitors

Overview of attention for article published in Breast Cancer Research, May 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (85th percentile)
  • Good Attention Score compared to outputs of the same age and source (65th percentile)

Mentioned by

news
1 news outlet

Citations

dimensions_citation
89 Dimensions

Readers on

mendeley
72 Mendeley
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Title
The expression and significance of insulin-like growth factor-1 receptor and its pathway on breast cancer stem/progenitors
Published in
Breast Cancer Research, May 2013
DOI 10.1186/bcr3423
Pubmed ID
Authors

Wen-Wei Chang, Ruey-Jen Lin, John Yu, Wen-Ying Chang, Chiung-Hui Fu, Alan Chuan-Ying Lai, Jyh-Cherng Yu, Alice L Yu

Abstract

Dysregulation of the insulin-like growth factor-1 receptor (IGF-1R)/phosphatidylinositol-3-kinase (PI3K)/Akt pathway was shown to correlate with breast cancer disease progression. Cancer stem cells are a subpopulation within cancer cells that participate in tumor initiation, radio/chemoresistance and metastasis. In breast cancer, breast cancer stem cells (BCSCs) were identified as CD24-CD44+ cells or cells with high intracellular aldehyde dehydrogenase activity (ALDH+). Elucidation of the role of IGF-1R in BCSCs is crucial to the design of breast cancer therapies targeting BCSCs.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 72 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 18%
Student > Master 11 15%
Student > Bachelor 10 14%
Student > Doctoral Student 8 11%
Researcher 7 10%
Other 13 18%
Unknown 10 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 20 28%
Medicine and Dentistry 19 26%
Biochemistry, Genetics and Molecular Biology 7 10%
Unspecified 3 4%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Other 8 11%
Unknown 13 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 January 2015.
All research outputs
#3,415,510
of 25,374,917 outputs
Outputs from Breast Cancer Research
#378
of 2,053 outputs
Outputs of similar age
#28,297
of 205,246 outputs
Outputs of similar age from Breast Cancer Research
#8
of 26 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,053 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 205,246 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 26 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.