Title |
Streptococcus agalactiae meningoencephalitis associated with gastroesophageal reflux disease and chronic proton pump inhibitors use, in a 9 month-old infant: a case report
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Published in |
BMC Pediatrics, February 2018
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DOI | 10.1186/s12887-018-0995-0 |
Pubmed ID | |
Authors |
Victoria Bîrluţiu, Codruța Mihaela Luca, Rareș-Mircea Bîrluțiu |
Abstract |
Streptococcus agalactiae (Group B Streptococcus) is recognized as the etiologic agent of newborn and infant meningitis, aged up to 90 days, starting from the colonization of the maternal genital or gastrointestinal tract, but it is rarely responsible for meningitis in old infants. We present the case of a 9 month-old infant diagnosed with S. agalactiae meningoencephalitis associated with chronic gastroesophageal reflux disease treated with a proton pump inhibitor (PPI). The use of a PPI is a risk factor for ultra-late onset of Group B Streptococcus meningitis. The use of PPI in infants should be closely monitored in the light of changes in the gut microbiota, in the oropharyngeal and of the respiratory tract colonization, potentially with pathogenic flora. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 43 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 8 | 19% |
Other | 5 | 12% |
Student > Master | 5 | 12% |
Student > Ph. D. Student | 3 | 7% |
Student > Bachelor | 2 | 5% |
Other | 3 | 7% |
Unknown | 17 | 40% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 7 | 16% |
Biochemistry, Genetics and Molecular Biology | 3 | 7% |
Nursing and Health Professions | 3 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 7% |
Neuroscience | 3 | 7% |
Other | 7 | 16% |
Unknown | 17 | 40% |