Title |
Metabolic correlates of health-related quality of life among overweight and obese adolescents
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Published in |
BMC Pediatrics, February 2018
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DOI | 10.1186/s12887-018-1044-8 |
Pubmed ID | |
Authors |
Chih-Ting Lee, Chung-Ying Lin, Carol Strong, Yu-Fang Lin, Yen-Yin Chou, Meng-Che Tsai |
Abstract |
Little is known about the metabolic factors associated with the health-related quality of life (HRQOL) among obese youths. The aim of this study is to assess metabolic correlates of HRQOL in a clinical sample of Taiwanese overweight and obese (OW/OB) adolescents. OW/OB adolescents (age 11-19 years) were recruited and compared to their normal-weight counterparts in a tertiary hospital. HRQOL was assessed by the Pediatric Quality of Life Inventory (PedsQL). Student t tests and Cohen's d were used to compare the differences in the PedsQL scores between normal-weight and OW/OB participants who were stratified by their cumulative number of cardiometabolic risk factors (CRF). Pearson's correlation and multivariate linear regression analyses were applied to identify predictors of PedsQL. OW/OB adolescents (n = 60) reported lower PedsQL scores than those of normal-weight peers. The negative effects were even larger in OW/OB participants with more than one CRF. Body mass index z-scores and serum alanine aminotransferase (ALT) levels were negatively correlated with overall and subscales of PedsQL (r = - 0.283 to - 0.431). Multivariate linear models showed ALT to be the most salient factor associated with poor obesity-related HRQOL. Taiwanese OW/OB adolescents, particularly those having additional CRF, reported worse HRQOL. Impaired liver functions may predispose OW/OB subjects to even worse HRQOL. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 48 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 11 | 23% |
Student > Master | 5 | 10% |
Student > Postgraduate | 4 | 8% |
Student > Doctoral Student | 3 | 6% |
Other | 2 | 4% |
Other | 6 | 13% |
Unknown | 17 | 35% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 10 | 21% |
Nursing and Health Professions | 5 | 10% |
Environmental Science | 1 | 2% |
Biochemistry, Genetics and Molecular Biology | 1 | 2% |
Arts and Humanities | 1 | 2% |
Other | 7 | 15% |
Unknown | 23 | 48% |