Title |
Locational distribution of gene functional classes in Arabidopsis thaliana
|
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Published in |
BMC Bioinformatics, March 2007
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DOI | 10.1186/1471-2105-8-112 |
Pubmed ID | |
Authors |
Michael C Riley, Amanda Clare, Ross D King |
Abstract |
We are interested in understanding the locational distribution of genes and their functions in genomes, as this distribution has both functional and evolutionary significance. Gene locational distribution is known to be affected by various evolutionary processes, with tandem duplication thought to be the main process producing clustering of homologous sequences. Recent research has found clustering of protein structural families in the human genome, even when genes identified as tandem duplicates have been removed from the data. However, this previous research was hindered as they were unable to analyse small sample sizes. This is a challenge for bioinformatics as more specific functional classes have fewer examples and conventional statistical analyses of these small data sets often produces unsatisfactory results. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | 5% |
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Unknown | 17 | 89% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 8 | 42% |
Student > Ph. D. Student | 4 | 21% |
Professor > Associate Professor | 2 | 11% |
Student > Master | 2 | 11% |
Lecturer | 1 | 5% |
Other | 1 | 5% |
Unknown | 1 | 5% |
Readers by discipline | Count | As % |
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Computer Science | 3 | 16% |
Biochemistry, Genetics and Molecular Biology | 1 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 5% |
Physics and Astronomy | 1 | 5% |
Other | 1 | 5% |
Unknown | 2 | 11% |