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Mesenchymal stem cells in the osteosarcoma microenvironment: their biological properties, influence on tumor growth, and therapeutic implications

Overview of attention for article published in Stem Cell Research & Therapy, January 2018
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Title
Mesenchymal stem cells in the osteosarcoma microenvironment: their biological properties, influence on tumor growth, and therapeutic implications
Published in
Stem Cell Research & Therapy, January 2018
DOI 10.1186/s13287-018-0780-x
Pubmed ID
Authors

Ying Zheng, Gangyang Wang, Ruiling Chen, Yingqi Hua, Zhengdong Cai

Abstract

During tumorigenesis and development, participation of the tumor microenvironment is not negligible. As an important component in the tumor microenvironment, mesenchymal stem cells (MSCs) have been corroborated to mediate proliferation, metastasis, and drug resistance in many cancers, including osteosarcoma. What's more, because of tumor site tropism, MSCs can be engineered to be loaded with therapeutic agents so that drugs can be precisely delivered to tumor lesions. In this review, we mainly discuss recent advances concerning the functions of MSCs in osteosarcoma and their possible clinical applications in the future.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 115 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 115 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 15 13%
Student > Master 14 12%
Student > Ph. D. Student 13 11%
Researcher 10 9%
Student > Postgraduate 9 8%
Other 14 12%
Unknown 40 35%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 27 23%
Medicine and Dentistry 19 17%
Agricultural and Biological Sciences 8 7%
Immunology and Microbiology 3 3%
Engineering 3 3%
Other 11 10%
Unknown 44 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 February 2018.
All research outputs
#15,490,822
of 23,020,670 outputs
Outputs from Stem Cell Research & Therapy
#1,353
of 2,429 outputs
Outputs of similar age
#269,584
of 440,210 outputs
Outputs of similar age from Stem Cell Research & Therapy
#39
of 58 outputs
Altmetric has tracked 23,020,670 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,429 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 440,210 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 29th percentile – i.e., 29% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.