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Comparative genomics reveals a widespread distribution of an exopolysaccharide biosynthesis gene cluster among Vibrionaceae

Overview of attention for article published in BMC Research Notes, February 2018
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Title
Comparative genomics reveals a widespread distribution of an exopolysaccharide biosynthesis gene cluster among Vibrionaceae
Published in
BMC Research Notes, February 2018
DOI 10.1186/s13104-018-3214-z
Pubmed ID
Authors

Lou Lebellenger, Véronique Verrez-Bagnis, Delphine Passerini, Christine Delbarre-Ladrat

Abstract

The eps locus in Vibrio diabolicus is involved in the production of the biotechnologically valuable HE800 EPS. In this study, the distribution and diversity of similar eps gene clusters across Vibrionaceae and its variability in relation to phylogenetic relationship were investigated. The aim was to provide a better knowledge of the eps gene cluster importance and to facilitate discovery of new EPS with potent interesting bioactivities. Seventy percent of the 103 genome sequences examined display such an eps locus with a high level of synteny. However, genetic divergence was found inside some monophyletic clades or even between some strains of the same species. It includes gene insertions, truncations, and deletions. Comparative analysis also reveals some variations in glycosyltransferase and export systems genes. Phylogenetic analysis of the Vibrionaceae eps gene clusters within Vibrionaceae suggests a vertical transfer by speciation but also pinpoints rearrangement events independent of the speciation.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 19 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 6 32%
Student > Ph. D. Student 3 16%
Student > Doctoral Student 3 16%
Student > Postgraduate 2 11%
Student > Master 1 5%
Other 1 5%
Unknown 3 16%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 7 37%
Engineering 2 11%
Veterinary Science and Veterinary Medicine 1 5%
Agricultural and Biological Sciences 1 5%
Psychology 1 5%
Other 3 16%
Unknown 4 21%