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Multiorgan eosinophilic infiltration after initiation of clozapine therapy: a case report

Overview of attention for article published in BMC Research Notes, July 2017
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Title
Multiorgan eosinophilic infiltration after initiation of clozapine therapy: a case report
Published in
BMC Research Notes, July 2017
DOI 10.1186/s13104-017-2662-1
Pubmed ID
Authors

Dorota Marchel, Anita L. Hart, Patricia Keefer, Jennifer Vredeveld

Abstract

The eosinophilic response to clozapine is well described in the literature, causing a variety of responses, from serositis to colitis. However, there are not case reports describing a clozapine-induced marked eosinophilia resulting in multiorgan dysfunction. In this case report, we describe a 24 year old Caucasian male who presented with severe systemic eosinophilia resulting in eosinophilic GI tract infiltration, myocarditis, pericardial and pleural effusions with dramatic improvement following drug withdrawal. Clozapine associated eosinophilia should be suspected in the setting of eosinophilic infiltration of multiple organs.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 12 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 25%
Student > Ph. D. Student 2 17%
Student > Bachelor 1 8%
Student > Postgraduate 1 8%
Unknown 5 42%
Readers by discipline Count As %
Medicine and Dentistry 4 33%
Nursing and Health Professions 1 8%
Pharmacology, Toxicology and Pharmaceutical Science 1 8%
Unknown 6 50%