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Adenosine deaminases acting on RNA (ADARs): RNA-editing enzymes

Overview of attention for article published in Genome Biology, February 2004
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1 Wikipedia page

Citations

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124 Dimensions

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125 Mendeley
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Title
Adenosine deaminases acting on RNA (ADARs): RNA-editing enzymes
Published in
Genome Biology, February 2004
DOI 10.1186/gb-2004-5-2-209
Pubmed ID
Authors

Liam P Keegan, Anne Leroy, Duncan Sproul, Mary A O'Connell

Abstract

Adenosine deaminases acting on RNA (ADARs) were discovered as a result of their ability extensively to deaminate adenosines in any long double-stranded RNA, converting them to inosines. Subsequently, ADARs were found to deaminate adenosines site-specifically within the coding sequences of transcripts encoding ion-channel subunits, increasing the diversity of these proteins in the central nervous system. ADARI is now known to be involved in defending the genome against viruses, and it may affect RNA interference. ADARs are found in animals but are not known in other organisms. It appears that ADARs evolved from a member of another family, adenosine deaminases acting on tRNAs (ADATs), by steps including fusion of two or more double-stranded-RNA binding domains to a common type of zinc-containing adenosine-deaminase domain.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 125 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Indonesia 1 <1%
United Kingdom 1 <1%
United States 1 <1%
Portugal 1 <1%
Unknown 121 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 29 23%
Researcher 16 13%
Student > Master 14 11%
Student > Bachelor 11 9%
Student > Doctoral Student 8 6%
Other 22 18%
Unknown 25 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 43 34%
Biochemistry, Genetics and Molecular Biology 38 30%
Immunology and Microbiology 4 3%
Medicine and Dentistry 4 3%
Engineering 3 2%
Other 7 6%
Unknown 26 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 December 2007.
All research outputs
#8,534,528
of 25,373,627 outputs
Outputs from Genome Biology
#3,489
of 4,467 outputs
Outputs of similar age
#37,568
of 146,588 outputs
Outputs of similar age from Genome Biology
#8
of 18 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one is in the 14th percentile – i.e., 14% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 146,588 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.