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Mendeley readers
Attention Score in Context
| Title |
TRIM5α selectively binds a restriction-sensitive retroviral capsid
|
|---|---|
| Published in |
Retrovirology, June 2005
|
| DOI | 10.1186/1742-4690-2-40 |
| Pubmed ID | |
| Authors |
Sarah Sebastian, Jeremy Luban |
| Abstract |
TRIM5 is a potent retrovirus inhibitor that targets viruses bearing particular capsid (CA) residues. In most primate species, retroviral restriction requires the C-terminal SPRY domain unique to the alpha-isoform of TRIM5, but the mechanism by which susceptible viruses are recognized and targeted for restriction is unknown. Here we show that TRIM5alpha binds retroviral CA from detergent-stripped virions in a SPRY-dependent manner with sufficient discrimination to account for the exquisite specificity of restriction. |
Mendeley readers
The data shown below were compiled from readership statistics for 99 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 2% |
| United Kingdom | 1 | 1% |
| South Africa | 1 | 1% |
| Brazil | 1 | 1% |
| Unknown | 94 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 28 | 28% |
| Researcher | 18 | 18% |
| Student > Bachelor | 16 | 16% |
| Student > Master | 14 | 14% |
| Student > Doctoral Student | 3 | 3% |
| Other | 9 | 9% |
| Unknown | 11 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 37 | 37% |
| Biochemistry, Genetics and Molecular Biology | 26 | 26% |
| Immunology and Microbiology | 9 | 9% |
| Medicine and Dentistry | 7 | 7% |
| Chemistry | 2 | 2% |
| Other | 3 | 3% |
| Unknown | 15 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 June 2021.
All research outputs
#2,270,301
of 22,785,242 outputs
Outputs from Retrovirology
#98
of 1,106 outputs
Outputs of similar age
#3,727
of 56,639 outputs
Outputs of similar age from Retrovirology
#1
of 4 outputs
Altmetric has tracked 22,785,242 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,106 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 56,639 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them