↓ Skip to main content

Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells

Overview of attention for article published in Breast Cancer Research, August 2004
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • Good Attention Score compared to outputs of the same age and source (72nd percentile)

Mentioned by

patent
18 patents
wikipedia
11 Wikipedia pages

Citations

dimensions_citation
640 Dimensions

Readers on

mendeley
386 Mendeley
connotea
1 Connotea
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells
Published in
Breast Cancer Research, August 2004
DOI 10.1186/bcr920
Pubmed ID
Authors

Gabriela Dontu, Kyle W Jackson, Erin McNicholas, Mari J Kawamura, Wissam M Abdallah, Max S Wicha

Abstract

Notch signaling has been implicated in the regulation of cell-fate decisions such as self-renewal of adult stem cells and differentiation of progenitor cells along a particular lineage. Moreover, depending on the cellular and developmental context, the Notch pathway acts as a regulator of cell survival and cell proliferation. Abnormal expression of Notch receptors has been found in different types of epithelial metaplastic lesions and neoplastic lesions, suggesting that Notch may act as a proto-oncogene. The vertebrate Notch1 and Notch4 homologs are involved in normal development of the mammary gland, and mutated forms of these genes are associated with development of mouse mammary tumors.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 386 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 4 1%
Canada 3 <1%
Spain 2 <1%
United States 2 <1%
Portugal 2 <1%
Italy 1 <1%
Greece 1 <1%
India 1 <1%
Unknown 370 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 105 27%
Researcher 63 16%
Student > Master 55 14%
Student > Bachelor 32 8%
Professor > Associate Professor 23 6%
Other 54 14%
Unknown 54 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 148 38%
Biochemistry, Genetics and Molecular Biology 72 19%
Medicine and Dentistry 54 14%
Engineering 11 3%
Chemistry 6 2%
Other 28 7%
Unknown 67 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 December 2023.
All research outputs
#3,798,287
of 25,373,627 outputs
Outputs from Breast Cancer Research
#451
of 2,052 outputs
Outputs of similar age
#5,396
of 55,417 outputs
Outputs of similar age from Breast Cancer Research
#3
of 11 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,052 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 55,417 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.