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Genome-wide conserved consensus transcription factor binding motifs are hyper-methylated

Overview of attention for article published in BMC Genomics, September 2010
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (68th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (57th percentile)

Mentioned by

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3 X users
wikipedia
2 Wikipedia pages

Readers on

mendeley
199 Mendeley
citeulike
5 CiteULike
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1 Connotea
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Title
Genome-wide conserved consensus transcription factor binding motifs are hyper-methylated
Published in
BMC Genomics, September 2010
DOI 10.1186/1471-2164-11-519
Pubmed ID
Authors

Mun-Kit Choy, Mehregan Movassagh, Hock-Guan Goh, Martin R Bennett, Thomas A Down, Roger SY Foo

Abstract

DNA methylation can regulate gene expression by modulating the interaction between DNA and proteins or protein complexes. Conserved consensus motifs exist across the human genome ("predicted transcription factor binding sites": "predicted TFBS") but the large majority of these are proven by chromatin immunoprecipitation and high throughput sequencing (ChIP-seq) not to be biological transcription factor binding sites ("empirical TFBS"). We hypothesize that DNA methylation at conserved consensus motifs prevents promiscuous or disorderly transcription factor binding.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 199 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 5 3%
United Kingdom 2 1%
France 1 <1%
Norway 1 <1%
Sweden 1 <1%
Italy 1 <1%
Ireland 1 <1%
Denmark 1 <1%
Belgium 1 <1%
Other 2 1%
Unknown 183 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 50 25%
Researcher 38 19%
Student > Master 36 18%
Student > Bachelor 25 13%
Student > Doctoral Student 10 5%
Other 26 13%
Unknown 14 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 99 50%
Biochemistry, Genetics and Molecular Biology 42 21%
Medicine and Dentistry 19 10%
Computer Science 4 2%
Engineering 3 2%
Other 14 7%
Unknown 18 9%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 February 2024.
All research outputs
#6,996,305
of 25,284,710 outputs
Outputs from BMC Genomics
#2,814
of 11,211 outputs
Outputs of similar age
#32,930
of 104,786 outputs
Outputs of similar age from BMC Genomics
#20
of 45 outputs
Altmetric has tracked 25,284,710 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 11,211 research outputs from this source. They receive a mean Attention Score of 4.8. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 104,786 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.
We're also able to compare this research output to 45 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.