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Isolation and characterization of cidofovir resistant vaccinia viruses

Overview of attention for article published in Virology Journal, May 2008
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Title
Isolation and characterization of cidofovir resistant vaccinia viruses
Published in
Virology Journal, May 2008
DOI 10.1186/1743-422x-5-58
Pubmed ID
Authors

Marie N Becker, Maria Obraztsova, Earl R Kern, Debra C Quenelle, Kathy A Keith, Mark N Prichard, Ming Luo, Richard W Moyer

Abstract

The emergence of drug resistant viruses, together with the possibility of increased virulence, is an important concern in the development of new antiviral compounds. Cidofovir (CDV) is a phosphonate nucleotide that is approved for use against cytomegalovirus retinitis and for the emergency treatment of smallpox or complications following vaccination. One mode of action for CDV has been demonstrated to be the inhibition of the viral DNA polymerase.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 10%
Unknown 9 90%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 50%
Student > Doctoral Student 2 20%
Student > Bachelor 1 10%
Student > Master 1 10%
Unknown 1 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 5 50%
Biochemistry, Genetics and Molecular Biology 1 10%
Immunology and Microbiology 1 10%
Medicine and Dentistry 1 10%
Unknown 2 20%