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Mendeley readers
| Title |
Recombinant human activated protein C resets thrombin generation in patients with severe sepsis – a case control study
|
|---|---|
| Published in |
Critical Care, July 2005
|
| DOI | 10.1186/cc3774 |
| Pubmed ID | |
| Authors |
Anne-Cornélie JM de Pont, Kamran Bakhtiari, Barbara A Hutten, Evert de Jonge, Margreeth B Vroom, Joost CM Meijers, Harry R Büller, Marcel Levi |
| Abstract |
Recombinant human activated protein C (rhAPC) is the first drug for which a reduction of mortality in severe sepsis has been demonstrated. However, the mechanism by which this reduction in mortality is achieved is still not clearly defined. The aim of the present study was to evaluate the dynamics of the anticoagulant, anti-inflammatory and pro-fibrinolytic action of rhAPC in patients with severe sepsis, by comparing rhAPC-treated patients with case controls. |
Mendeley readers
The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Italy | 1 | 4% |
| Brazil | 1 | 4% |
| Unknown | 24 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 4 | 15% |
| Researcher | 4 | 15% |
| Student > Master | 4 | 15% |
| Student > Ph. D. Student | 3 | 12% |
| Professor | 3 | 12% |
| Other | 6 | 23% |
| Unknown | 2 | 8% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 16 | 62% |
| Biochemistry, Genetics and Molecular Biology | 3 | 12% |
| Agricultural and Biological Sciences | 3 | 12% |
| Arts and Humanities | 1 | 4% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 4% |
| Other | 2 | 8% |