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Relationship between gut hormones and glucose homeostasis after bariatric surgery

Overview of attention for article published in Diabetology & Metabolic Syndrome, August 2014
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Citations

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33 Dimensions

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94 Mendeley
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Title
Relationship between gut hormones and glucose homeostasis after bariatric surgery
Published in
Diabetology & Metabolic Syndrome, August 2014
DOI 10.1186/1758-5996-6-87
Pubmed ID
Authors

Priscila Campos Sala, Raquel Susana Torrinhas, Daniel Giannella-Neto, Dan Linetzky Waitzberg

Abstract

Type 2 diabetes mellitus (T2D) is emerging as a worldwide public health problem, and is mainly associated with an increased incidence of obesity. Bariatric surgery is currently considered the most effective treatment for severely obese patients. After bariatric surgery, T2D patients have shown a significant improvement in glycemic control, even before substantial weight loss and often discontinuation of medication for diabetes control. A central role for enteroendocrine cells from the epithelium of the gastrointestinal tract has been speculated in this postoperative phenomenon. These cells produce and secrete polypeptides - gut hormones - that are associated with regulating energy intake and glucose homeostasis through modulation of peripheral target organs, including the endocrine pancreas. This article reviews and discusses the biological actions of the gut hormones ghrelin, cholecystokinin, incretins, enteroglucagon, and Peptide YY, all of which were recently identified as potential candidates for mediators of glycemic control after bariatric surgery. In conclusion, current data reinforce the hypothesis that T2D reversion after bariatric surgery may be related to glycemic homeostasis developed by the intestine.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 94 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 1%
Unknown 93 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 16%
Student > Postgraduate 13 14%
Student > Master 13 14%
Student > Doctoral Student 8 9%
Student > Bachelor 8 9%
Other 21 22%
Unknown 16 17%
Readers by discipline Count As %
Medicine and Dentistry 47 50%
Agricultural and Biological Sciences 9 10%
Biochemistry, Genetics and Molecular Biology 7 7%
Pharmacology, Toxicology and Pharmaceutical Science 2 2%
Veterinary Science and Veterinary Medicine 2 2%
Other 7 7%
Unknown 20 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 January 2017.
All research outputs
#17,743,721
of 22,786,087 outputs
Outputs from Diabetology & Metabolic Syndrome
#432
of 663 outputs
Outputs of similar age
#141,071
of 209,898 outputs
Outputs of similar age from Diabetology & Metabolic Syndrome
#7
of 22 outputs
Altmetric has tracked 22,786,087 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 663 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.1. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 209,898 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.