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CGRP and migraine: neurogenic inflammation revisited

Overview of attention for article published in The Journal of Headache and Pain, April 2005
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (93rd percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

news
1 news outlet
patent
30 patents
wikipedia
3 Wikipedia pages

Readers on

mendeley
75 Mendeley
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Title
CGRP and migraine: neurogenic inflammation revisited
Published in
The Journal of Headache and Pain, April 2005
DOI 10.1007/s10194-005-0153-6
Pubmed ID
Authors

P. Geppetti, J. G. Capone, M. Trevisani, P. Nicoletti, G. Zagli, M. R. Tola

Abstract

For more than a century neurogenic inflammation has been proposed to have a role in various human diseases. The present review will cover the conceptual steps of the itinerary that has led to the conclusion that neurogenic inflammation is important in migraine. Of particular relevance for the object of this article is the observation that tachykin-independent neurogenic inflammatory responses are evident in rodents, but much less pronounced or absent in other mammal species, including man, whereas neurogenic vasodilatation, most likely mediated by CGRP, occurs in most mammalian species and also in man. Recent evidence that a CGRP receptor antagonist was effective in the treatment of migraine attack supports the hypothesis that neurogenic vasodilatation is a major underlying mechanism of migraine.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 1%
United States 1 1%
Canada 1 1%
Unknown 72 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 17%
Student > Ph. D. Student 12 16%
Student > Master 10 13%
Student > Bachelor 7 9%
Student > Postgraduate 6 8%
Other 16 21%
Unknown 11 15%
Readers by discipline Count As %
Medicine and Dentistry 24 32%
Agricultural and Biological Sciences 14 19%
Neuroscience 9 12%
Biochemistry, Genetics and Molecular Biology 7 9%
Pharmacology, Toxicology and Pharmaceutical Science 6 8%
Other 3 4%
Unknown 12 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 May 2023.
All research outputs
#2,423,054
of 23,849,058 outputs
Outputs from The Journal of Headache and Pain
#285
of 1,417 outputs
Outputs of similar age
#3,989
of 60,859 outputs
Outputs of similar age from The Journal of Headache and Pain
#1
of 5 outputs
Altmetric has tracked 23,849,058 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,417 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 17.6. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 60,859 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them