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Evidence of reduced treatment adherence among HIV infected paediatric and adolescent populations in Nairobi at the onset of the UNAIDS Universal Test and Treat Program

Overview of attention for article published in BMC Research Notes, February 2018
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Title
Evidence of reduced treatment adherence among HIV infected paediatric and adolescent populations in Nairobi at the onset of the UNAIDS Universal Test and Treat Program
Published in
BMC Research Notes, February 2018
DOI 10.1186/s13104-018-3205-0
Pubmed ID
Authors

Joseph Kabogo, Erastus Muniu, Fred Wamunyokoli, Rachel Musoke, Elijah Songok

Abstract

We conducted a retrospective cohort study to evaluate the efficacy of the World Health Organization (WHO) "Universal Test and Treat" (UTT) policy, initiated in Kenya in September 2016. Under this policy, every human immunodeficiency virus (HIV)-infected person should be initiated on antiretroviral therapy (ART). We compared intra- and inter-group viral suppression and ART adherence rates for pre-UTT (initiated on ART in March-August 2016) and UTT groups (initiated in September 2016). The study was conducted in a community outreach Program in Nairobi with 3500 HIV-infected children enrolled. 122 children and adolescents were initiated on first-line ART pre-UTT, and 197 during the UTT period. The 6 month viral suppression rate was 79.7% pre-UTT versus 76.6% UTT (P < 0.05). Suboptimal adherence was higher in the UTT than pre-UTT period (88 of 197, 44.7% and 44 of 122, 34%; P < 0.001). The decrease in adherence was greater among orphans (91.7% pre-UTT and 87.2% UTT, P = 0.001) and children 11-18 years. Our results show that successful implementation of the UTT policy in Africa is challenged by an increased risk of suboptimal adherence. There is a need to develop extra strategies to support adherence, especially among orphans and teenagers.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 79 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 79 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 22 28%
Student > Ph. D. Student 12 15%
Researcher 10 13%
Student > Bachelor 5 6%
Student > Postgraduate 4 5%
Other 10 13%
Unknown 16 20%
Readers by discipline Count As %
Medicine and Dentistry 25 32%
Nursing and Health Professions 15 19%
Social Sciences 5 6%
Psychology 4 5%
Agricultural and Biological Sciences 3 4%
Other 9 11%
Unknown 18 23%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 March 2018.
All research outputs
#11,245,557
of 12,633,553 outputs
Outputs from BMC Research Notes
#2,361
of 2,837 outputs
Outputs of similar age
#235,100
of 271,032 outputs
Outputs of similar age from BMC Research Notes
#1
of 1 outputs
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