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Early-life exposure to PM2.5 and risk of acute asthma clinical encounters among children in Massachusetts: a case-crossover analysis

Overview of attention for article published in Environmental Health, February 2018
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • Good Attention Score compared to outputs of the same age and source (70th percentile)

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Title
Early-life exposure to PM2.5 and risk of acute asthma clinical encounters among children in Massachusetts: a case-crossover analysis
Published in
Environmental Health, February 2018
DOI 10.1186/s12940-018-0361-6
Pubmed ID
Authors

Roxana Khalili, Scott M. Bartell, Xuefei Hu, Yang Liu, Howard H. Chang, Candice Belanoff, Matthew J. Strickland, Verónica M. Vieira

Abstract

Associations between ambient particulate matter < 2.5 μm (PM2.5) and asthma morbidity have been suggested in previous epidemiologic studies but results are inconsistent for areas with lower PM2.5levels. We estimated the associations between early-life short-term PM2.5exposure and the risk of asthma or wheeze clinical encounters among Massachusetts children in the innovative Pregnancy to Early Life Longitudinal (PELL) cohort data linkage system. We used a semi-bidirectional case-crossover study design with short-term exposure lags for asthma exacerbation using data from the PELL system. Cases included children up to 9 years of age who had a hospitalization, observational stay, or emergency department visit for asthma or wheeze between January 2001 and September 2009 (n = 33,387). Daily PM2.5concentrations were estimated at a 4-km resolution using satellite remote sensing, land use, and meteorological data. We applied conditional logistic regression models to estimate adjusted odds ratios (ORs) and 95% confidence intervals (CI). We also stratified by potential effect modifiers. The median PM2.5concentration among participants was 7.8 μg/m3with an interquartile range of 5.9 μg/m3. Overall, associations between PM2.5exposure and asthma clinical encounters among children at lags 0, 1 and 2 were close to the null value of OR = 1.0. Evidence of effect modification was observed by birthweight for lags 0, 1 and 2 (p < 0.05), and season of clinical encounter for lags 0 and 1 (p < 0.05). Children with low birthweight (LBW) (< 2500 g) had increased odds of having an asthma clinical encounter due to higher PM2.5exposure for lag 1 (OR: 1.08 per interquartile range (IQR) increase in PM2.5; 95% CI: 1.01, 1.15). Asthma or wheeze exacerbations among LBW children were associated with short-term increases in PM2.5concentrations at low levels in Massachusetts.

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X Demographics

The data shown below were collected from the profiles of 19 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 108 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 108 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 18 17%
Researcher 15 14%
Student > Ph. D. Student 14 13%
Student > Bachelor 9 8%
Other 5 5%
Other 8 7%
Unknown 39 36%
Readers by discipline Count As %
Medicine and Dentistry 14 13%
Nursing and Health Professions 11 10%
Engineering 7 6%
Social Sciences 7 6%
Environmental Science 6 6%
Other 18 17%
Unknown 45 42%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 February 2019.
All research outputs
#3,056,778
of 25,393,455 outputs
Outputs from Environmental Health
#533
of 1,601 outputs
Outputs of similar age
#59,834
of 337,630 outputs
Outputs of similar age from Environmental Health
#10
of 31 outputs
Altmetric has tracked 25,393,455 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,601 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 37.9. This one has gotten more attention than average, scoring higher than 66% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 337,630 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.