Title |
CoBaltDB: Complete bacterial and archaeal orfeomes subcellular localization database and associated resources
|
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Published in |
BMC Microbiology, March 2010
|
DOI | 10.1186/1471-2180-10-88 |
Pubmed ID | |
Authors |
David Goudenège, Stéphane Avner, Céline Lucchetti-Miganeh, Frédérique Barloy-Hubler |
Abstract |
The functions of proteins are strongly related to their localization in cell compartments (for example the cytoplasm or membranes) but the experimental determination of the sub-cellular localization of proteomes is laborious and expensive. A fast and low-cost alternative approach is in silico prediction, based on features of the protein primary sequences. However, biologists are confronted with a very large number of computational tools that use different methods that address various localization features with diverse specificities and sensitivities. As a result, exploiting these computer resources to predict protein localization accurately involves querying all tools and comparing every prediction output; this is a painstaking task. Therefore, we developed a comprehensive database, called CoBaltDB, that gathers all prediction outputs concerning complete prokaryotic proteomes. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 7% |
Sweden | 1 | 2% |
France | 1 | 2% |
Brazil | 1 | 2% |
Unknown | 39 | 87% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 10 | 22% |
Researcher | 10 | 22% |
Student > Master | 5 | 11% |
Student > Bachelor | 4 | 9% |
Professor > Associate Professor | 3 | 7% |
Other | 9 | 20% |
Unknown | 4 | 9% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 22 | 49% |
Computer Science | 5 | 11% |
Engineering | 4 | 9% |
Biochemistry, Genetics and Molecular Biology | 3 | 7% |
Business, Management and Accounting | 1 | 2% |
Other | 2 | 4% |
Unknown | 8 | 18% |