↓ Skip to main content

Mutations of PIK3CAin gastric adenocarcinoma

Overview of attention for article published in BMC Cancer, March 2005
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (85th percentile)
  • High Attention Score compared to outputs of the same age and source (83rd percentile)

Mentioned by

patent
6 patents
wikipedia
1 Wikipedia page

Citations

dimensions_citation
154 Dimensions

Readers on

mendeley
47 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Mutations of PIK3CAin gastric adenocarcinoma
Published in
BMC Cancer, March 2005
DOI 10.1186/1471-2407-5-29
Pubmed ID
Authors

Vivian Sze Wing Li, Chi Wai Wong, Tsun Leung Chan, Agnes Sze Wah Chan, Wei Zhao, Kent-Man Chu, Samuel So, Xin Chen, Siu Tsan Yuen, Suet Yi Leung

Abstract

Activation of the phosphatidylinositol 3-kinase (PI3K) through mutational inactivation of PTEN tumour suppressor gene is common in diverse cancer types, but rarely reported in gastric cancer. Recently, mutations in PIK3CA, which encodes the p110alpha catalytic subunit of PI3K, have been identified in various human cancers, including 3 of 12 gastric cancers. Eighty percent of these reported mutations clustered within 2 regions involving the helical and kinase domains. In vitro study on one of the "hot-spot" mutants has demonstrated it as an activating mutation.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
United States 1 2%
Unknown 45 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 21%
Researcher 9 19%
Student > Doctoral Student 4 9%
Lecturer 4 9%
Professor > Associate Professor 4 9%
Other 12 26%
Unknown 4 9%
Readers by discipline Count As %
Medicine and Dentistry 16 34%
Biochemistry, Genetics and Molecular Biology 12 26%
Agricultural and Biological Sciences 9 19%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Immunology and Microbiology 1 2%
Other 3 6%
Unknown 5 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 September 2023.
All research outputs
#3,602,989
of 24,447,003 outputs
Outputs from BMC Cancer
#876
of 8,667 outputs
Outputs of similar age
#6,667
of 61,878 outputs
Outputs of similar age from BMC Cancer
#1
of 6 outputs
Altmetric has tracked 24,447,003 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,667 research outputs from this source. They receive a mean Attention Score of 4.5. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 61,878 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them